Investigation of the Antibacterial Activity of a Chloroform Extract of Ling Zhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W. Curt.: Fr.) P. Karst. (Aphyllophoromycetideae), from Iran

Keypour, Somayeh; Riahi, Hossein; Moradali, Mohammad-Fata; Rafati, Hasan

doi:10.1615/intjmedmushr.v10.i4.70

Cited by 40 publications

(32 citation statements)

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“…All the polysaccharide samples tested in our study show the broad spectrum of antibacterial activity, covering both Gram-positive and Gram-negative strains, however, the power of this activity is moderate. Our results are in agreement with other studies reporting the moderate activity and the broad antimicrobial spectrum of the different extracts from G. lucidum [17,32,33]. Its polysaccharides are confirmed to be the bioactive components, which show the significant antibacterial activity.…”

Section: Resultssupporting

confidence: 93%

Evaluation of polysaccharides content in fruit bodies and their antimicrobial activity of four Ganoderma lucidum (W Curt.: Fr.) P. Karst. strains cultivated on different wood type substrates

et al. 2012

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Quantitative determination of polysaccharides in Ganoderma lucidum fruit bodies from different sawdust cultivation substrates and their antibacterial activity was done. Thirty six samples were analyzed. Four strains of Ganoderma lucidum (GL01, GL02, GL03 and GL04) were cultivated on the growth substrates of three different sawdust types: birch (Bo), maple (Kl) or alder (Ol) amended with wheat bran in three different concentrations: 10, 20 and 30% (w/w). Even though the richest in polysaccharides was GL01 strain, the highest yields of the polysaccharides were determined in GL04Kl3 sample and was 112.82 mg/g of dry weight. The antibacterial activity of polysaccharides was determined in vitro using micro-dilution broth method. The panel of eight reference bacterial strains was used. All the polysaccharide samples tested showed the broad spectrum and the moderate antibacterial activity. Micrococcus luteus ATCC 10240 strain was the most sensitive with MIC (minimal inhibitory concentration) = 0.63 − 1.25 mg/mL

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Section: Resultssupporting

confidence: 93%

Evaluation of polysaccharides content in fruit bodies and their antimicrobial activity of four Ganoderma lucidum (W Curt.: Fr.) P. Karst. strains cultivated on different wood type substrates

et al. 2012

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“…A study 35 have shown a high MIC value of 8 mg/ml of the chloroform extract for S. aureus and B. subtilis strains which is quite high in comparison to MIC value obtained by us indicating that the aqueous and the hydro alcoholic extracts possess more potential as an antibacterial agent at lower concentrations against the multi drug resistant pathogens.…”

Section: Antimicrobial Activity and Mic Of The Plant Extractmentioning

confidence: 73%

Untitled

2015

IJPSR

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Ganoderma lucidum (Fr.) Karst., known as medicinal mushroom and it contains several bioactive phytochemicals such as polysaccharides, nucleosides, alkaloids, coumarin, ergosterols, ganoderic acids, lactones, mannitol, organic germanium, triterpenoids, unsaturated fatty acids, vitamins and minerals which are well known for their pharmacological properties. In the present investigation adenine, adenosine and uracil content of the aqueous and alcoholic lyophilized extract of dried G. lucidum powder of Indian Himalayan Region (IHR) were determined by HPTLC. Further, phytochemical analysis (total polyphenols, total flavonoids, reducing power, antioxidant potentials), antioxidant and antimicrobial efficacy of both extracts against pathogenic strains like Vibrio cholerae, methicillin resistant Staphylococcus aureus, Bacillus subtilis and Bacillus cereus was also evaluated. The adenine, adenosine and uracil content of aqueous extract was found to be higher than the alcoholic extracts. Both extracts were identified as rich source of flavonoids, polyphenols, reducing power and antioxidants. A significant antimicrobial activity was observed in both the hydro alcoholic and aqueous extract against all the pathogenic strains tested with MIC value of 2-4 mg/ml for the hydro alcoholic extract and of 2-5 mg/ml for the aqueous extract. The present study concludes high pharmacological potential of G. lucidum.

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“…Macromycetes extracts contain lots of active chemical compounds which show potential antimicrobial activities. For example, terpenes, organic acids, benzoic acid derivates and quinolone were isolated from some species such as Ganoderma spp., Lentinus edodes and Leucopaxillus albissimus showed activity against many different species of bacteria and yeast [1,10,[15][16][17][18].…”

Section: Discussionmentioning

confidence: 99%

Investigation of Antimicrobial Activity of Different Trametes versicolor Extracts on Some Clinical Isolates

Özgör¹,

Ulusoy²,

Celebier³

et al. 2016

HJBC

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Ö Z E T K linik önemi olan ve ciddi hastalıklara sebep olan türlere karşı yoğun ilaç kullanımı bu türlerde direnç gelişimini tetiklemektedir. İlerleyen yıllarda birçok antimikrobiyal ilaç etkisiz hale geleceğinden bu türlere karşı yeni potansiyel ilaçların keşfedilmesi gereklidir. Anahtar KelimelerTrametes versicolor, Antimikrobiyal aktivite, Antifungal aktivite, Klinik izolatlar. A B S T R A C TI ntensive drug uses against species which have clinical significance and cause severe diseases have triggered the development of resistance in these species. It is necessary to discover new potential drugs against clinical isolates because many antimicrobial drugs become ineffective in the coming years. In this research, we used different extracts from Trametes versicolor fruiting bodies for investigating antibacterial and antifungal activities on some clinical isolates. For this purpose, five bacterial species (Staphylococcus aureus, Enterococcus faecalis, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa) and a fungal species (Candida albicans) were selected as clinically important isolates and four different crude extracts (chloroform, water, ethyl acetate and ethyl alcohol) of Trametes versicolor were tried on these species in terms of antimicrobial sensitivity with disc diffusion method. Obtained data were analyzed using SPSS 14 software. At the result, some of extracts were found to have antimicrobial activity on clinical isolates although all extracts generally show antimicrobial effect. Chloroform extract was found to have the highest antimicrobial activity on S. aureus and E. faecalis while ethanol extract was observed as more effective on P. aeruginosa, E. coli, B. subtilis and C. albicans isolates. It can therefore be suggested that, some of Trametes versicolor extracts are promising antimicrobial agents.

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Investigation of the Antibacterial Activity of a Chloroform Extract of Ling Zhi or Reishi Medicinal Mushroom, Ganoderma lucidum (W. Curt.: Fr.) P. Karst. (Aphyllophoromycetideae), from Iran

Cited by 40 publications

References 0 publications

Evaluation of polysaccharides content in fruit bodies and their antimicrobial activity of four Ganoderma lucidum (W Curt.: Fr.) P. Karst. strains cultivated on different wood type substrates

Evaluation of polysaccharides content in fruit bodies and their antimicrobial activity of four Ganoderma lucidum (W Curt.: Fr.) P. Karst. strains cultivated on different wood type substrates

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Investigation of Antimicrobial Activity of Different Trametes versicolor Extracts on Some Clinical Isolates

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