Investigation of the 8-hydroxy-2′-deoxyguanosine, total antioxidant and nitric oxide levels of serum in dogs infected with Babesia vogeli

Çiftçi, Gülay; Ural, Kerem; Aysul, Nuran; Çenesiz, Sena; Güzel, Murat Erdem; Pekmezci, Didem; Söğüt, Mehtap Ünlü

doi:10.1016/j.vetpar.2014.05.002

Cited by 9 publications

(9 citation statements)

References 14 publications

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“…These results agree with those reported earlier in sheep (38), and dogs infested by babesiosis (32). Furthermore, Ciftci et al (39) observed that TAC levels decreased in Babesia vogeli infested dogs, but these variations were not found as statistically significant (P>0.05). However, Crnogaj et al (34) obtained a TAC values which were significantly lower in dogs infested by Babesia canis canis compared to controls.…”

Section: Discussionsupporting

confidence: 92%

Hematological and Oxidative Status Parameters in Domestic Dogs Naturally Infested by Rhipicephalus Sp.

Kebbi

Besseboua

Belhadj-Kebbi

et al. 2020

Macedonian Veterinary Review

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The present study was aimed to evaluate hematological and oxidative stress parameters in domestic dogs infested naturally (n=10) by Rhipicephalus sp. to compare with non-infested dogs (n=10). All blood samples were collected from brachial vein into tubes EDTA for the hematological analysis such as red blood cells (RBCs), white blood cells (WBCs), hemoglobin (HGB) and platelets (PLT). Serum was rapidly separated after centrifugation and stored at -20 °C until it was used for malondialdehyde (MDA) and 2,2’-Azinobis-(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS) inhibition measurements. HGB in non-infested dogs was significantly higher than in infested dogs (P<0.05). There was no significant difference in RBCs, WBCs and PLT between both groups (P>0.05). The mean of MDA concentration was high in infested dogs (0.92±0.62 nmol/ml) compared to non-infested dogs (0.75±0.25 nmol/ml). On the other hand, the percentage of ABTS inhibition was similar in both groups (P=0.71). High tick number seems significantly affected WBCs (P<0.0001) and HGB (P<0.001) in infested dogs. Concerning oxidative status, there was no significant differences (P>0.05) between low and high infested dogs, neither in the amount of MDA nor in the ABTS inhibition. In conclusion, infested dogs induced RBCs alterations, which coincided with the oxidative damage, as evidenced by MDA serum levels. Also, there was a relationship between the tick number in infested dogs and the hematological parameters.

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Section: Discussionsupporting

confidence: 92%

Hematological and Oxidative Status Parameters in Domestic Dogs Naturally Infested by Rhipicephalus Sp.

Kebbi

Besseboua

Belhadj-Kebbi

et al. 2020

Macedonian Veterinary Review

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“…The decrease in PON1 could also indicate the presence of an oxidative stress in these diseases as it has been demonstrated in feline infectious peritonitis . Similarly, in dogs, development of oxidative stress has been reported in infections with H canis and B vogeli . Nonetheless, determination of other biomarkers of oxidant/antioxidant status in cats would better clarify this topic.…”

Section: Total Number Sex Age and Breeds Of Cats Included In The Smentioning

confidence: 82%

Acute phase proteins response in cats naturally infected with Hepatozoon felis and Babesia vogeli

Vilhena

Tvarijonaviciute

Cerón

et al. 2017

Veterinary Clinical Pathol

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“…In addition, an assay using horseradish peroxidase (HRP) as an enzyme source to produce ABTS• + more efficiently (assay C) has been described. 4,5 In dogs, when assay A was used to measure TAC, no differences between healthy dogs and dogs with different diseases such as heart disease, 14 atopic dermatitis, 16 and babesiosis 8 were detected. However, the assay was capable of detecting lower TAC values in dogs with symptomatic leishmaniasis.…”

Section: Introductionmentioning

confidence: 98%

Validation of three automated assays for total antioxidant capacity determination in canine serum samples

et al. 2016

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We performed analytical validation of 3 automated assays of the total antioxidant capacity (TAC) in canine serum and evaluated their use in dogs with inflammatory bowel disease. The assays were based on the generation of a 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) radical cation (ABTS•) in aqueous media, which produces a blue-green color. The antioxidants present in the sample remove the chromogen in proportion to their concentrations. The assays differed mainly in the way in which this radical was produced. All 3 assays produced acceptable results in the analytical validation. However, only 2 of the assays were capable of detecting significantly different TAC values in healthy and diseased animals.

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Investigation of the 8-hydroxy-2′-deoxyguanosine, total antioxidant and nitric oxide levels of serum in dogs infected with Babesia vogeli

Cited by 9 publications

References 14 publications

Hematological and Oxidative Status Parameters in Domestic Dogs Naturally Infested by Rhipicephalus Sp.

Hematological and Oxidative Status Parameters in Domestic Dogs Naturally Infested by Rhipicephalus Sp.

Acute phase proteins response in cats naturally infected with Hepatozoon felis and Babesia vogeli

Validation of three automated assays for total antioxidant capacity determination in canine serum samples

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