Investigation of statistics strategies for improving the discriminating power of laser-induced breakdown spectroscopy for chemical and biological warfare agent simulants

Munson, Chase A.; Lucia, Frank C. De; Piehler, Thuvan; McNesby, Kevin L.; Miziolek, Andrzej W.

doi:10.1016/j.sab.2005.05.017

Cited by 128 publications

(73 citation statements)

References 21 publications

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“…Munson et al 339 investigated the efficiency of sample identification using LIBS coupled with various statistical techniques, such as linear correlation, PCA and SIMCA. The influence of data selection, sample averaging, spectral weighting, LIBS laser power and the sample matrix on the ability of these statistical models to perform species differentiation was studied.…”

Section: Chemometrics Applicationsmentioning

confidence: 99%

Laser Induced Breakdown Spectroscopy

Pasquini¹,

Cortez²,

Silva³

et al. 2007

J. Braz. Chem. Soc.

326

195

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Esta revisão descreve os aspectos fundamentais, a instrumentação, as aplicações e tendências futuras de uma técnica analítica que se encontra em seu estágio de consolidação e que está em vias de estabelecer o seu nicho entre as técnicas espectrofotométricas modernas. A técnica é denominada Espectroscopia de Emissão em Plasma Induzido por Laser (em inglês, Laser Induced Breakdown Spectroscopy, LIBS) e sua principal característica está no uso de pulsos de laser como fonte de energia para vaporizar a amostra e excitar a emissão de radiação eletromagnética, a partir de seus elementos e/ou fragmentos moleculares. A radiação emitida é analisada por meio de instrumentos ópticos de alta resolução e as suas intensidades são medidas, usualmente com detectores rápidos de estado sólido. Em conjunto, esses dispositivos permitem a geração e a medida de um espectro de emissão de faixa ampla do fenômeno induzido pelo pulso de laser. O espectro registrado contém informação qualitativa e quantitativa que pode ser correlacionada com a identidade da amostra ou empregada na determinação da quantidade de seus constituintes. Essa revisão é dividida em quatro partes. A primeira aborda aspectos históricos da técnica e os conceitos teóricos relevantes associados com LIBS; então, os aspectos práticos de diversas abordagens experimentais e instrumentais empregadas na implementação da técnica são revistos de forma crítica; as aplicações encontradas na literatura, incluindo aquelas que empregam quimiometria, são classificadas e exemplificadas por meio de trabalhos relevantes recentemente publicados. Finalmente, uma tentativa de estabelecer uma avaliação global e as perspectivas futuras para a técnica é apresentada.This review describes the fundamentals, instrumentation, applications and future trends of an analytical technique that is in its early stages of consolidation and is establishing its definitive niches among modern spectrometric techniques. The technique has been named Laser Induced Breakdown Spectroscopy (LIBS) and its main characteristic stands in the use of short laser pulses as the energy source to vaporize samples and excite the emission of electromagnetic radiation from its elements and/or molecular fragments. The emitted radiation is analyzed by high resolution optics and the intensities are recorded, usually by fast triggered solid state detectors. Together, these devices allow producing and registering a wide ranging emission spectrum of the short-lived phenomenon induced by the laser pulse. The spectrum contains qualitative and quantitative information which can be correlated with sample identity or can be used to determine the amount of its constituents. This review is divided in four parts. First, the relevant historical and theoretical concepts associated with LIBS are presented; then the main practical aspects of the several experimental and instrumental approaches employed for implementation of the technique are critically described; the applications related in the literature, including those making use of chemometri...

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Section: Chemometrics Applicationsmentioning

confidence: 99%

Laser Induced Breakdown Spectroscopy

Pasquini¹,

Cortez²,

Silva³

et al. 2007

J. Braz. Chem. Soc.

326

195

View full text Add to dashboard Cite

show abstract

“…The use of computerized chemometric techniques like DFA, principal component analysis, or principal least squares-discriminant analysis has greatly increased the selectivity of the LIBS technique and reduced the time required to make identifications of unknown targets based on their LIBS spectra [29][30][31][32][33][34]. DFA is a statistical technique used for classifying a set of observations into mutually exclusive groups on the basis of a set of independent variables (predictors).…”

Section: E Data Analysismentioning

confidence: 99%

Towards the clinical application of laser-induced breakdown spectroscopy for rapid pathogen diagnosis: the effect of mixed cultures and sample dilution on bacterial identification

2010

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Rehse, Steven J.; Mohaidat, Q.I.; and Palchaudhuri, S.. (2010). Towards the clinical application of laser-induced breakdown spectroscopy for rapid pathogen diagnosis: The effect of mixed cultures and sample dilution on bacterial identification. Laser-induced breakdown spectroscopy has been utilized to classify and identify bacterial specimens on the basis of their atomic composition. We have characterized the effect that the presence of a second bacterial species in the ablated specimen had on the identification of the majority species. Specimens with a reduced number of bacterial cells (approximately 2500) were identified with 100% accuracy when compared to undiluted specimens. In addition, a linear dependence of the total spectral power as a function of cell number was determined. Lastly, a high selectivity was obtained for a LIBS-based analysis of nine separate bacterial strains from four genera.

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“…ARL has used LIBS for the detection of Halon alternative agents (19,20), tested a field-portable LIBS system for the detection of lead in soil and paint (10), studied the spectral emission of aluminum and aluminum oxide from bulk aluminum in different bath gases (21), performed kinetic modeling of LIBS plumes (22)(23)(24)(25), and demonstrated the detection and discrimination of geological materials (18,(26)(27)(28)(29)(30)(31), plastic landmines (32,33), explosives (34)(35)(36)(37)(38)(39)(40)(41)(42), and chemical and biological warfare agent surrogates (43)(44)(45)(46)(47). ARL has also published a number of reviews on LIBS (8,(48)(49)(50)(51)(52).…”

Section: Background/expertisementioning

confidence: 99%

“…With recent advances in broadband spectrometers and chemometric analysis techniques, the identification of non-metals has become increasingly widespread with LIBS. LIBS has been used for the identification of polymers (43)(44)(45)(46)(47)(48)(49)(50)(51)(52)(53)(54)(55)(56)(57), thermoplasts (58)(59)(60), and other organic compounds (61,62), including explosives (34)(35)(36)(37)(38)(39)(40)(41)(42)(63)(64)(65). Figure 4 shows the LIBS spectra of various thermoplastic polymers from McMaster-Carr acquired with a commercial LIBS system (Applied Photonics, Ltd).…”

Section: Identification Of Materialsmentioning

confidence: 99%

Laser-Induced Breakdown Spectroscopy: Capabilities and Applications

Gottfried¹,

Lucia²

2010

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Investigation of statistics strategies for improving the discriminating power of laser-induced breakdown spectroscopy for chemical and biological warfare agent simulants

Cited by 128 publications

References 21 publications

Laser Induced Breakdown Spectroscopy

Laser Induced Breakdown Spectroscopy

Towards the clinical application of laser-induced breakdown spectroscopy for rapid pathogen diagnosis: the effect of mixed cultures and sample dilution on bacterial identification

Laser-Induced Breakdown Spectroscopy: Capabilities and Applications

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