Investigation of Species Distribution and Antifungal Susceptibility of Candida Species Isolated from Various Clinical Samples From Intensive Care Unit Patients

Pelit, Süleyman; Uzun, Meltem

doi:10.5152/dcbybd.2016.1050

Cited by 3 publications

(1 citation statement)

References 13 publications

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“…According to the results of this study; C. albicans was found in the first place with (52.2%), followed by C. parapsilosis (22.1%), C. tropicalis (14.8%) and C. glabrata (6.6%). In the study carried out by Pelit et al, [18] when the distribution at species level was examined for a total of 121 Candida strains isolated from different cultures, (45 (37%) from blood cultures), C. albicans in 60 (49%), C. tropicalis in 21 (17.3%), C. parapsilosis in 17 (14%), C. glabrata in 15 (12%), C. keyfr in 3 (2.5%), C. krusei in 2 (1.7%), C. lusitaniae, C. famata and C. lipolytica in 1 were defined. The results of our study are in accordance with the above studies; C. albicans was found in the first place with 45.2% followed by C. parapsilosis 25.2% and C. tropicalis 14.7%.…”

Section: Discussionmentioning

confidence: 99%

Distribution of Candida species isolated from blood cultures over a period of four years

Akgün¹

2018

EJMI

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Objectives: Candida, which is an opportunistic pathogen, is becoming a cause of significant morbidity and mortality due to the infection it can cause, especially in patients at greater risk. The aim of the present study was to examine a total of 95 Candida isolates collected from blood cultures at a training and research hospital microbiology culture laboratory over approximately 4 years. Methods: This study included 95 Candida samples grown in blood cultures at the microbiology laboratory between 2014 and 2017. The samples were first seeded with 5% sheep blood agar and eosin methylene blue agar media. Next, those identified as yeast using conventional methods were isolated with Sabouraud Dextrose Agar. Subsequently, the strain was identified using a fully automated culture-antibiogram device. Results: Type distribution indicated that among the 95 Candida samples collected over 4 years, the most common strains were C. albicans (n=43; 45%) and C. parapsilosis (n=24; 25%), followed by C. tropicalis (n=14; 15%), C. glabrata (n=6; 6%), and C. kefyr (n=5; 5%). Conclusion: According to these results, although there was an increase in the number of other Candida species observed, C. albicans remains the most important pathogen.

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Section: Discussionmentioning

confidence: 99%

Distribution of Candida species isolated from blood cultures over a period of four years

Akgün¹

2018

EJMI

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Çeşitli örneklerden izole edilen Candidaların tür dağılımı ve antifungal direnç oranları

Savcı¹,

Yılmaz²

2018

TURKISH JOURNAL of CLINICS and LABORATORY

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Amaç: Bu çalışmada Bozok Üniversitesi Araştırma ve Uygulama Hastanesi'ne başvuran hastalara ait çeşitli klinik örneklerden izole edilen Candidaların tür dağılımları ve antifungal duyarlılık oranlarının belirlenmesi amaçlanmıştır. Gereç ve Yöntemler: Ekim 2014-Ocak 2016 tarihleri arasında Candida türleri izole edilen 42 adet klinik örnek retrospektif olarak değerlendirildi. İzolatların tanımlanmasında germ tüp testi ile ticari VITEK 2 Compact® (Biomerieux, France) maya identifikasyon sistemi kullanıldı. İzolatların antifungal duyarlılıkları flukonazol, vorikonazol, kaspofungin, mikafungin, amfoterisin B ve flusitozin antifungallerini içeren disposable VITEK 2 AST YS02 test kartları kullanılarak belirlendi. Bulgular: Çeşitli klinik örneklerden toplam 42 Candida türü izole edildi. C. albicans % 66,7 ile en sık soyutlanan tür olurken, non-albicans türler %33,3 oranında saptandı. C.albicans'ı sırasıyla C.glabrata (%11,9), C.kefyr (%7,1), C.tropicalis (%4,8), C.famata (%2,4), C.krusei (%2,4), C.lusitaniae (%2,4) ve C.spherica (%2,4) izledi. Tüm izolatların antifungal direnç oranları sırasıyla; flukonazol %14, flusitozin %3, vorikonazol %6, amfoterisin-B %5, kaspofungin %6, mikafungin %3 oranları belirlendi. C.albicans izolatlarında flukonazol direnç oranı %11 olarak saptandı. C.kefyr, C.lusitaniae ve C.tropicalis izolatlarında mevcut antifungallere direnç görülmedi. C.glabrata'nın antifungal direnç oranı diğer Candida türlerine göre daha yüksekti. Sonuçlar: Çalışmamızda en sık izole edilen C.albican'tan sonra gelen C.glabrata izolatlarının diğer Candida türlerine göre antifungal direncinin daha yüksek olduğu saptanmıştır. Son yıllarda non-albicans türlerin ve antifungal direnç oranlarının artması sebebiyle Candidaların tür düzeyinde tanımlanması ve antifungal duyarlılık testlerinin yapılmasının gerekliliği düşünülmektedir.

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The distrubution and antifungal susceptibilities of candida species isolated from clinical samples of intensive care unit patients

Altın¹,

Cesur

Toros³

et al. 2018

Ortadogu Tıp Derg

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Investigation of Species Distribution and Antifungal Susceptibility of Candida Species Isolated from Various Clinical Samples From Intensive Care Unit Patients

Cited by 3 publications

References 13 publications

Distribution of Candida species isolated from blood cultures over a period of four years

Distribution of Candida species isolated from blood cultures over a period of four years

Çeşitli örneklerden izole edilen Candidaların tür dağılımı ve antifungal direnç oranları

The distrubution and antifungal susceptibilities of candida species isolated from clinical samples of intensive care unit patients

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