Investigation of selenium speciation in in vitro gastrointestinal extracts of cooked cod by high-performance liquid chromatography–inductively coupled plasma mass spectrometry and electrospray mass spectrometry

Crews, Helen M.; Clarke, Philip A.; Lewis, D. John; Owen, Linda; Strutt, Paul R.; Izquierdo, A.

doi:10.1039/ja9961101177

Cited by 111 publications

(68 citation statements)

References 35 publications

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“…The inductively coupled plasma mass spectrometer (ICP-MS ) is an effective element specific HPLC detector which has been applied to a number of selenium speciation studies [22,[33][34][35][36][37][38][39]. In this paper, as part of an ongoing study of the cancer chemopreventive activity of selenium, extracts of selenium containing samples are analyzed by HPLC-ICP-MS and by chloroformate derivatization GC-AED.…”

Section: Introductionmentioning

confidence: 99%

Analytical selenoamino acid studies by chromatography with interfaced atomic mass spectrometry and atomic emission spectral detection

Uden

Bird

Kotrebai

et al. 1998

Fresenius' Journal of Analytical Chemistry

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Section: Introductionmentioning

confidence: 99%

Analytical selenoamino acid studies by chromatography with interfaced atomic mass spectrometry and atomic emission spectral detection

Uden

Bird

Kotrebai

et al. 1998

Fresenius' Journal of Analytical Chemistry

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“…So far, ESI MS has been applied mostly to commercial standards [30,83] or synthetic preparations of Se-methylselenomethionine, Se-methylselenocysteine, and dimethylselenonium propionate (precursors of volatile alkylselenides) [29]. Recently, improved pneumatically-assisted ESI MS was used to identify Se-adenosyl-homocysteine in an extract of selenized yeast [21].…”

Section: Identification Of Selenium Speciesmentioning

confidence: 99%

“…The employed separation mechanisms have included ion-exchange (anion and cation) and ionpairing reversed-phase chromatography, the degree of separation being strongly dependent on the pH of the mobile phase [17,30,58,61]. Anion-exchange [20] and cation-exchange [55] are complementary separation mechanisms, neither of which used alone are able to assure satisfactory resolution of all the seleno compounds in extracts of biological samples.…”

Section: Detection Of Small Seleno Compounds By Hplc-icp Msmentioning

confidence: 99%

“…However, except for simple compounds such as selenate, selenite, selenomethionine, selenocysteine, and selenoethionine, authentic standards of selenium compounds are rarely available. The major approaches to address this problem are based on the (i) preparation of synthetic standards and retention (migration) time matching, and (ii) isolation of the purified seleno compound from the sample for its further characterization, e.g., by electrospray (ES) [21,[23][24][25]29,30,83]) or matrix-assisted laser desorption ionization (MALDI) [50].…”

Section: Identification Of Selenium Speciesmentioning

confidence: 99%

“…Among the six organoselenium compounds detected in seagull eggs the major compounds were selenocysteine and selenocystamine [27]. Another area of interest in species-selective determination of amino acids is their production by enzymolysis of selenoproteins [28][29][30][31]; this step is also a central one in sample preparation of selenium materials for HPLC determination.…”

Section: Species Of Interestmentioning

confidence: 99%

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Species-selective determination of selenium compounds in biological materials (Technical Report)

Łobiński

Edmonds

Suzuki

et al. 2000

Pure and Applied Chemistry

157

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Republication or reproduction of this report or its storage and/or dissemination by electronic means is permitted without the need for formal IUPAC permission on condition that an acknowledgmentMembership of the Commission during the preparation of this report (1997)(1998)(1999) Species-selective determination of selenium compounds in biological materials (Technical Report)Abstract: There is substantial evidence of the complexity of selenium speciation in living organisms and of the importance of the selective determination of the particular species of this element in order to understand its metabolism and biological significance in clinical chemistry, biology, toxicology, and nutrition. The state-of-the-art of analytical techniques available for this purpose is critically evaluated with particular emphasis on the element-selective detection and identification of the detected selenium compounds. Whereas there are a number of techniques available that are able to detect various selenium species in living organisms selectively, few techniques exist that are able to identify and to characterize the species detected.

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Electrospray mass spectrometry of trimethyllead and triethyllead with in-tube solid phase microextraction sample introduction

Mester¹,

Pawliszyn

1999

Rapid Commun. Mass Spectrom.

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A study of positive ionization electrospray mass spectrometry (ES-MS) was performed on trimethyllead (TML) and triethyllead (TEL). The system consisted of in-tube solid phase microextraction (SPME) coupled directly to an electrospray mass spectrometer. Fragmentation patterns of compounds were observed by applying different fragmentation voltages. High voltages produced sufficient fragmentation to elucidate the dissociation of the trialkyllead compounds. Electrospray mass spectrometry has been shown to be a suitable detection system for organolead speciation. Applying fragmentation energy programming, it might be possible to obtain in parallel the molecular and atomic signals of lead compounds. Copyright 1999 John Wiley & Sons, Ltd.

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Investigation of selenium speciation in in vitro gastrointestinal extracts of cooked cod by high-performance liquid chromatography–inductively coupled plasma mass spectrometry and electrospray mass spectrometry

Cited by 111 publications

References 35 publications

Analytical selenoamino acid studies by chromatography with interfaced atomic mass spectrometry and atomic emission spectral detection

Analytical selenoamino acid studies by chromatography with interfaced atomic mass spectrometry and atomic emission spectral detection

Species-selective determination of selenium compounds in biological materials (Technical Report)

Electrospray mass spectrometry of trimethyllead and triethyllead with in-tube solid phase microextraction sample introduction

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