Investigation of reactive extraction of monocarboxylic acids with menthol-based hydrophobic deep eutectic solvent by response surface methodology

Yıldız, Esra; Lalikoğlu, Melisa; Aşçı, Yavuz Selim; Tarım, Burcu Sırma

doi:10.1080/01496395.2023.2192382

Cited by 4 publications

(2 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The efficiency of reactive extraction depends on the physical and chemical characteristics of the solute: hydrophobicity and acid-base properties; on the properties of the extractant: reactivity, the ability to form hydrophobic compounds with the solute, and on separation conditions: pH, mixing intensity, concentration level, etc. Due to these conditions, the interaction mechanism between solute and extractant, the optimal extraction conditions in correlation with the separation factors, and the extraction mechanism are the main directions of study in reactive extraction [37][38][39]. The mechanism of reactive extraction presents particularities specific to each extraction system, the general case being presented in Figure 3 [12].…”

Section: Reactive Extractionmentioning

confidence: 99%

Recent Advances in Muconic Acid Extraction Process

Blaga,

Gal,

Tucaliuc

2023

Applied Sciences

View full text Add to dashboard Cite

Due to its potential use in the production of new functional resins, bio-plastics, food additives, agrochemicals, and pharmaceuticals, muconic acid (MA), a high value-added bio-product with reactive dicarboxylic groups and conjugated double bonds, has attracted growing interest. Adipic acid, terephthalic acid, and trimellitic acid are examples of bulk compounds that can be produced using MA that are of high commercial importance. The development of biotechnological approaches for MA production has advanced greatly recently. The current analysis offers a thorough and organized summary of recent developments and difficulties in the extraction of MA. A variety of extractants are presented, along with any limitations and potential solutions. Finally, the possibilities for this field in light of its state, difficulties, and tendencies are explored.

show abstract

Section: Reactive Extractionmentioning

confidence: 99%

Recent Advances in Muconic Acid Extraction Process

Blaga,

Gal,

Tucaliuc

2023

Applied Sciences

View full text Add to dashboard Cite

show abstract

“…As a promising method for IA separation, reactive extraction, derived from liquidliquid separation methods, is a process that involves the transfer of a solute from one liquid phase to another immiscible phase, facilitated by an extractant. This method is especially useful for separating compounds with similar physical properties or when conventional separation techniques like distillation or crystallization are not effective or economically viable [7]. Reactive extraction is commonly employed for efficiently separating organic acids, leading to improved results [8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

Studies on Reactive Extraction of Itaconic Acid from Fermentation Broths

Blaga,

Kloetzer,

Cascaval

et al. 2024

Processes

View full text Add to dashboard Cite

Itaconic acid is a high-value organic acid that serves as a platform molecule in different industries. This research focuses on the separation of itaconic acid using reactive extraction as a sustainable and efficient method for acid recovery from fermentation broth. Itaconic acid was produced through fungal fermentation processes involving Aspergillus terreus ATCC® 32588™, obtaining a concentration of 47 g/L in the final broths. For the reactive extraction system, the organic phase included tri-n-octylamine as an extractant dissolved in dichloromethane or n-heptane and 1-octanol as a phase modifier. The effect of the main influencing factors (pH of the aqueous phase, extractant concentrations in the organic phase, and the addition of 1-octanol) on extraction efficiency was investigated. The highest extraction degree (97%) was achieved using an organic phase with tri-n-octylamine dissolved in dichloromethane and with 20% 1-octanol. Conversely, in the reactive extraction system with tri-n-octylamine dissolved in n-heptane and 20% 1-octanol, the extraction efficiency reached 67%. This finding suggests a promising separation system that is less toxic for microorganisms. The study results highlight the feasibility of employing reactive extraction systems for the direct separation of itaconic acid.

show abstract

Choline chloride based natural deep eutectic solvents coupling with ultra-high performance liquid chromatography-tandem mass spectroscopy for effective extraction and rapid detection of adenosine and cordycepin in Cordyceps millitaris

Nguyen,

Tran

et al. 2024

Journal of Molecular Liquids

View full text Add to dashboard Cite

Investigation of reactive extraction of monocarboxylic acids with menthol-based hydrophobic deep eutectic solvent by response surface methodology

Cited by 4 publications

References 40 publications

Recent Advances in Muconic Acid Extraction Process

Recent Advances in Muconic Acid Extraction Process

Studies on Reactive Extraction of Itaconic Acid from Fermentation Broths

Choline chloride based natural deep eutectic solvents coupling with ultra-high performance liquid chromatography-tandem mass spectroscopy for effective extraction and rapid detection of adenosine and cordycepin in Cordyceps millitaris

Contact Info

Product

Resources

About