Diatoms are unique photoautotrophic microalgae, in which the outer cell wall is composed of a silici ed skeletal structure called frustules. These microalgae have relatively higher generation times and growth rates than other groups of microalgae. An interesting feature is that the diatom can accumulate a greater volume of heavy metals in its frustule, and have some specialized proteins and enzymes for detoxi cation of heavy metals. In the present study, a centric diatom was isolated from the Adyar River, Chennai, Tamil Nadu, India, and morphologically identi ed as Cyclotella atomus Hust. Based on the bioaccumulation study on the treatment with TiO 2 with culturing the diatom Cyclotella atomus and SEM-EDAX analysis it has resulted that, the Ti accumulated on the frustules of the diatom. Therefore, biogenic accumulation and fabrication of Titanium frustules in diatom have advantages in enhancing the e ciency of solar cells.