Investigation of novel benzimidazole-based indole/thiazole hybrids derivatives as effective anti-diabetics and anti-alzheimer's agents: Structure-activity relationship insight, in vitro and in silico approaches

Naz, Haseena; Othman, Mohamed S.; Rahim, Fazal; Hussain, Rafaqat; Khan, Shoaib; Taha, Muhammad; Hafez, Mohamed M.; Abdel-Hafez, Lina JM; Ullah, Hayat; Khan, Ihsan Ullah; Khan, Yousaf; Shah, Syed Adnan Ali

doi:10.1016/j.molstruc.2024.138592

Journal of Molecular Structure

2024

DOI: 10.1016/j.molstruc.2024.138592

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Investigation of novel benzimidazole-based indole/thiazole hybrids derivatives as effective anti-diabetics and anti-alzheimer's agents: Structure-activity relationship insight, in vitro and in silico approaches

Haseena Naz,

Mohamed S. Othman,

Fazal Rahim

et al.

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Cited by 3 publications

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Investigation of novel benzimidazole-based indole/thiazole hybrids derivatives as effective anti-diabetics and anti-alzheimer's agents: Structure-activity relationship insight, in vitro and in silico approaches

Cited by 3 publications

References 51 publications

Synthesis and biological evaluation of substituted benzohydrazide Schiff base adduct as potential cholinesterase inhibitors

Synthesis and biological evaluation of substituted benzohydrazide Schiff base adduct as potential cholinesterase inhibitors

Design, Synthesis, in vitro biological evaluation and in silico molecular docking study of chloro substituted Benzimidazole-Thiazole hybrid derivatives as potential Anti-Alzheimer’s agents

Design, synthesis and in vitro biological evaluation of new coumarin containing oxazole hybrid derivatives as multitarget inhibitor of α-amylase and α-glucosidase for the treatment of diabetes

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