Investigation of Neurotoxic and Immunotoxic Effects of the Chinar (Platanus orientalis L.) Tree Leaf Infusion Against Ethanol Toxicity in Rats

Doğan, Abdulahad; Dönmez, Fatih; Battal, Abdulhamit; Aslan, Ali; Anuk, Özgür Ozan

doi:10.21597/jist.643987

Cited by 3 publications

(2 citation statements)

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“…Medicinal plants and their bioactive compounds are used against immunotoxic and neurotoxic damage caused by chemicals, pesticides and heavy metals (Dogan et al, 2020). Ozok and Celik (2019), in their study to determine the immunotoxic effects of Tiliaplatyphyllos Scop plant infusion of ethanol in rats, stated that ADA activity in liver tissue decreased significantly, and the plant extract had a positive effect on enzyme activity with its antioxidant effect.…”

Section: Resultsmentioning

confidence: 99%

“…It has been reported that there are two types of cholinesterase in the body, AChE and BChE (Gulcin et al, 2016;Turkan 2021).Similarly, adenosineaminase and myeloperoxidase are biomarkers of the immune system in vertebrates. While ADA is an enzyme that catabolizes adenosine or deoxyadenosine, MPO is an enzyme that catalyzes the formation of hypochlorous acid or hypothiocyanide (Tamura et al, 2016;Lu et al, 2018;Dogan et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

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Determination Effects of Rheum ribes L. against High Calorie Diet-induced Obesity: Investigation of Changes in Immunologic and Neurologic Enzymes Activities

Batı

2022

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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This study was carried out to investigate the immunotoxic and neurotoxic effects of Rheum ribes L. (Rr) plant extract on liver, brain and heart tissues in rats with an experimental obesity model. Wistar albino male rats were used in the study. In this study, 4 groups were formed, one of which was the control group, and each group consisted of 6 rats. The groups were the ''control (CG)'', ''high calorie diet (HCD) control (HCDG)'', 'HCD + Rr (200 mg/kg) (HCDRHE1)'' and ''HCD + Rr (400 mg/kg) (HCDRHE2)''. At the end of the study, acetylcholinesterase (AChE), butyrylcholinesterase (BChE), adenosineaminase (ADA) and myeloperoxidase (MPO) biomarkers were evaluated in tissues. According to the study findings, the ADA and MPO activity levels of the obese group increased significantly compared to the control group, and these enzyme levels in the groups administered Rr plant extract approached the control group levels. On the other hand, the AChE and BChE activity levels of the obese group decreased compared to the control group, and there was a statistically significant increase in the groups administered plant extracts compared to the control group. In conclusion, Rr plant root extract suppresses neurotoxicity and immunotoxicity in rats with obesity induced by a high-calorie diet (HCD).

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Determination Effects of Rheum ribes L. against High Calorie Diet-induced Obesity: Investigation of Changes in Immunologic and Neurologic Enzymes Activities

Batı

2022

Iğdır Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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Investigation of the effects of three different generations of fluoroquinolone derivatives on antioxidant and immunotoxic enzyme levels in different rat tissues

Dönmez

Doğan

2021

Drug and Chemical Toxicology

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Volatile constituents of oriental plane tree (Platanus orientalis L.) leaves

KAYTANLIOĞLU

Fakir

Dönmez

2022

Turkish Journal of Forestry | Türkiye Ormancılık Dergisi

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Oriental Plane tree is a very monumental, flamboyant and broad-topped tree belonging to the Platanaceae family. Deciduous plane trees, which can reach 55 meters in length and 6 meters in trunk diameter, mostly spread around water and near water. Oriental Plane trees are used in big cities for landscape and aesthetic purposes, and their wood is used for interior furniture. Fabric dye is obtained from branches and roots. Oriental plane tree leaves are collected by the public for natural tea. In this study, leaf volatile constituents of the leaves of the oriental plane tree were determined. Samples were collected from two different points within the borders of Isparta, leaf samples were dried at room temperature, and their volatile constituents were determined by HS-SPME / GC-MS analysis. Analyzes were applied in the local sample of Sütçüler and Yenişarbademli, 43 in the sample. The most active volatile constituents in the volatile constituents of oriental plane tree leaves of Sütçüler region: (21.76%) (E) -2-Hexenal, (8.14%) n-Hexanal, (7.27%) benzaldehyde, Yenişarbademli region the most active volatile constituents of the oriental plane tree leaves: (16.96%) (E) -2-hexenal, (11.75%) n-hexanal, (7.09%) cis-3-hexene-1-ol.

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Investigation of Neurotoxic and Immunotoxic Effects of the Chinar (Platanus orientalis L.) Tree Leaf Infusion Against Ethanol Toxicity in Rats

Cited by 3 publications

References 38 publications

Determination Effects of Rheum ribes L. against High Calorie Diet-induced Obesity: Investigation of Changes in Immunologic and Neurologic Enzymes Activities

Determination Effects of Rheum ribes L. against High Calorie Diet-induced Obesity: Investigation of Changes in Immunologic and Neurologic Enzymes Activities

Investigation of the effects of three different generations of fluoroquinolone derivatives on antioxidant and immunotoxic enzyme levels in different rat tissues

Volatile constituents of oriental plane tree (Platanus orientalis L.) leaves

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