Investigation of monodisperse droplet generation in liquids by inkjet

Zeng, Hulie; Yang, Jianming; Katagiri, Daisuke; Rang, Ying; Xue, Shuhua; Nakajima, Hirochika; Uchiyama, Katsumi

doi:10.1016/j.snb.2015.06.027

Cited by 16 publications

(14 citation statements)

References 24 publications

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“…given their ability to move in aqueous media in presence of chemical triggers (surfactant concentration gradient, solid-liquid interfacial tension and other ones). [36][37][38] In this regard, IJP represents an ideal approach for producing oil droplets on demand, as firstly demonstrated by Zeng and collaborators [215] who inkjet printed oil droplets at sizes comprised in the hundreds of microns (210-290 μm). Their inkjet nozzles were immersed in the water phase, and the size of the droplets was tuned by varying the applied voltage and the pulse width exerted on the piezo actuator.…”

Section: Primitive Autonomous Objectsmentioning

confidence: 98%

Artificial Biosystems by Printing Biology

Arrabito

Ferrara

Bonasera

et al. 2020

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The continuous progress of printing technologies over the past 20 years has fueled the development of a wide plethora of applications in materials sciences, flexible electronics and biotechnologies. More recently, printing methodologies have started up to explore the world of Artificial Biology, offering new paradigms in the direct assembly of Artificial Biosystems (small condensates, compartments, networks, tissues and organs) by mimicking the result of the evolution of living systems and also by redesigning natural biological systems, taking inspiration from them. This recent progress is reported in terms of a new field here defined as Printing Biology, resulting from the intersection between the field of printing and the bottom up Synthetic Biology. Printing Biology explores new approaches for the reconfigurable assembly of designed lifelike or life-inspired structures. This review presents this emerging field, highlighting its main features, i.e. printing methodologies (from 2D to 3D), molecular ink properties, deposition mechanisms, and finally the applications and future challenges. Printing Biology is expected to show a growing impact on the development of biotechnology and lifeinspired fabrication. Printing Biology employs different technologies dispensing molecular inks with tunable composition (molecules, polymers, biomolecules) and drop sizes (from nano-up to macroscale) onto solids or into liquids to develop lifelike or life-inspired artificial biosystems (from small condensates, to compartments up to networks, tissues and organs). This work reviews the extraordinary potential of this emerging research field.

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Section: Primitive Autonomous Objectsmentioning

confidence: 98%

Artificial Biosystems by Printing Biology

Arrabito

Ferrara

Bonasera

et al. 2020

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“…Furthermore, they successfully loaded them with DOX, permitting a pH-responsive delivery to tumor cells (B16F10 and 4T1) at similar levels compared to free administrated DOX [155] (Figure 4H). As in the case of microfluidic systems, in 2018, the inkjet printing technologies [156] were employed for emulsion preparations, [157][158][159] and implemented for vesicle assembly, with high reproducibility and size control.…”

Section: Microfluidics and Printing Approachesmentioning

confidence: 99%

Mastering the Tools: Natural versus Artificial Vesicles in Nanomedicine

Leggio

Arrabito

Ferrara

et al. 2020

Adv Healthcare Materials

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Naturally occurring extracellular vesicles and artificially made vesicles represent important tools in nanomedicine for the efficient delivery of biomolecules and drugs. Since its first appearance in the literature 50 years ago, the research on vesicles is progressing at a fast pace, with the main goal of developing carriers able to protect cargoes from degradation, as well as to deliver them in a time‐ and space‐controlled fashion. While natural occurring vesicles have the advantage of being fully compatible with their host, artificial vesicles can be easily synthetized and functionalized according to the target to reach. Research is striving to merge the advantages of natural and artificial vesicles, in order to provide a new generation of highly performing vesicles, which would improve the therapeutic index of transported molecules. This progress report summarizes current manufacturing techniques used to produce both natural and artificial vesicles, exploring the promises and pitfalls of the different production processes. Finally, pros and cons of natural versus artificial vesicles are discussed and compared, with special regard toward the current applications of both kinds of vesicles in the healthcare field.

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“…[71,72] . 一系列研究表明, 基于静电驱动、压电陶瓷形变驱动的喷墨打印技术能够实现单个活细胞液滴的快速制备, 且不会对细胞活性造成明显影响 [73,74] . [88] , 并且对该方法制备的中空胶囊的通透性和电导性能进行了进一步研究 [89,90] .…”

Section: 的综述性文章报道较少 Jeroen Leijten等人综述了单unclassified