Investigation of microfluidic co-flow effects on step emulsification: Interfacial tension and flow velocities

Lian, Jiaoyuan; Luo, Xingfang; Huang, Xing; Wang, Yuehui; Xu, Zhongbin; Ruan, Xiangyan

doi:10.1016/j.colsurfa.2019.02.040

Cited by 19 publications

(6 citation statements)

References 53 publications

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“…Lian et al 30 reported one innovative solution to overcome the fixed droplet size in step emulsification by integrating a co-flow module at the nozzle outlet. Despite being a creative approach to extend the capabilities of step emulsification, it came with the drawbacks of co-flow systems, such as i) relying on changes of flow rates to modify the droplet sizes and ii) the challenging parallelization that would require separate channels of continuous phase for each nozzle.…”

Section: Discussionmentioning

confidence: 99%

Tuna-step: tunable parallelized step emulsification for the generation of droplets with dynamic volume control to 3D print functionally graded porous materials

Nalin,

Tirelli,

Garstecki

et al. 2024

Lab Chip

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Section: Discussionmentioning

confidence: 99%

Tuna-step: tunable parallelized step emulsification for the generation of droplets with dynamic volume control to 3D print functionally graded porous materials

Nalin,

Tirelli,

Garstecki

et al. 2024

Lab Chip

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“…Micro uidic droplet generated methods often needs chip microchannels which is rstly obtained by photo-lithographical microfabrication. However, microfabrication is limited by cleanroom environment, professional facilities and operator (Lian et al 2019; Nie et al 2019). In addition, the fact that types of the droplets are in uenced by the inherent surface wettability of the microchannel would also limits its universality and exibility (Lee et al 2003; Toepke and Beebe 2006;Whitesides 2006).…”

Section: Introductionmentioning

confidence: 99%

A Floating Capillary Based Open Microfluidic Device for Stable and On- Demand Generation of Monodispersed Emulsion Droplets

Deng,

Xie,

Yang

et al. 2024

Preprint

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Simple and stable generation of monodispersed droplets with volume from picolitre to nanoliter is one of the key factors in high-throughput quantitative microreactors for chemical and biomedical applications. In this work, a floating capillary based open microfluidic device (FCOMD) is constructed by inserting a capillary with an oblique angle (α) into the continuous phase (CP) to develop a simple method for preparation of monodispersed droplet. The geometrical parameters, including inner diameter and α, present a strong correlation for the controllability of droplet breakage and thus its volume. According to the microfluidic experiments, the mechanism of breakup of dispersed phase (DP) into droplets in the FCOMD was proposed from the aspect of energy. The transition of droplet generating mode between dripping and jetting can be achieved by changing the DP capillary number and α. Water in oil (W/O), oil in water (O/W), double-emulsion, colloidal dispersed droplets and liquid crystal droplets with diameter ranges from 25–800 µm (CVs under 2%) are prepared on-demand by the FCOMD. To improve the generating throughput, different numbers of capillaries are integrated for an integrated FCOMD. This FCOMD shows the features of simple, stable, practicable, and flexible, showing a great potential application in material science, foods, pharmaceuticals and cosmetics.

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“…Stauffer et al (2019) modified the wetting properties of the microchip to generate microdroplets with controlled size and shell thickness. Lian et al (2019) investigated the effect of microfluidic interfacial tension on the stepwise emulsification of microdroplets by numerical simulations using ANSYS Fluent. Zhao-Miao et al (2018) used a combination of experimental and numerical simulations to investigate the effects of the flow rate of three phases on the forming pattern, size, and frequency of double emulsion droplets.…”

Section: Introductionmentioning

confidence: 99%

Research on the Effect of Geometric Parameters of a Six-Way Junction Microchannel on the Formation of a Double Emulsion Droplet

2023

JAFM

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As a typical microdroplet, double emulsion droplet, has received much attention and been widely used in recent years. For a simplified double-cross-shaped microchannel, the process of preparing double emulsion droplets is numerically simulated in this paper. The mechanism of droplet forming was analyzed, and the effects of the angles of the inner-, middle-, and outer-phase channels of the microchip, length of the focusing hole, and expansion angle on the process and quality of the double emulsion droplet formation were investigated. The variation in angles between each inlet channel affects the droplet area; the change in expansion angle affects the flow pattern of droplets; the change in each geometric parameter affects the monodispersity of droplets. The droplet area is fitted to the microchannel geometric parameters and the functional expressions that represent their relationship are derived. The work in this paper provides a reference for the practical production and research of double emulsion droplets.

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Investigation of microfluidic co-flow effects on step emulsification: Interfacial tension and flow velocities

Cited by 19 publications

References 53 publications

Tuna-step: tunable parallelized step emulsification for the generation of droplets with dynamic volume control to 3D print functionally graded porous materials

Tuna-step: tunable parallelized step emulsification for the generation of droplets with dynamic volume control to 3D print functionally graded porous materials

A Floating Capillary Based Open Microfluidic Device for Stable and On- Demand Generation of Monodispersed Emulsion Droplets

Research on the Effect of Geometric Parameters of a Six-Way Junction Microchannel on the Formation of a Double Emulsion Droplet

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