Investigation of killer cell immunoglobulinlike receptor gene diversity: I. KIR2DL4

Investigation of killer cell immunoglobulin-like receptor gene diversity: II. KIR2DS4

“…The A-C transversion at position 162 within exon 5 of KIR2DS4*005 is a silent mutation. [12,23]. Inevitably, techniques allowing discrimination of alleles belonging to individual KIR genes will provide a clearer picture with regard to the extent of polymorphism that exists within each of these genes.…”

Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China

“…Recent studies by several research groups of the KIR allelic frequencies, haplotype frequencies and linkage disequilibrium of different populations have compared their data with a number of other results obtained from different populations observed previously [32,59,60]. These groups concluded that the study of KIR gene frequencies and haplotypes in different groups have an important meaning in the interpretation of national and racial traceability [32,59,60].…”

“…These groups concluded that the study of KIR gene frequencies and haplotypes in different groups have an important meaning in the interpretation of national and racial traceability [32,59,60]. The neighbor-joining phylogenic tree showed that the Tibetan population was located in the Asian cluster, where it was the nearest to the Hong Kong Han in south China.…”

Killer cell immunoglobulin-like receptor allele discrimination by high-resolution melting

“…Samples subtyped as KIR2DL4*005 with our previous system [17] could be either *005 (10A allele) or *011 (9A allele) with the new nomenclature, and those originally typed as KIR2DL4*00201 or *00202 (10A) could be *00802 or *00801 (9A), respectively. Samples containing all alleles assigned by the previous system were selected to obtain clones representing each possible allele.…”