Investigation of interactions between host, pathogens, and probiotic bacteria

Mucosal immunity in mollusks

“…This protective effect has often been linked to the production of antibiotic compounds by probionts that inhibit the growth of pathogenic microbes, leading to the establishment of a robust beneficial mucosal microflora. The elegant studies by Dao et al (2012) and Abd used probiont mutants to demonstrate the implication of genes involved in biofilm formation in oyster protection from pathogenic bacteria. These authors also concluded that the production of antibiotic compounds is not a requirement for good probionts and that competitive exclusion and immune priming contribute to host protection.…”