Investigation of Hydrogel Skin Phantoms Using Terahertz Time-domain Spectroscopy

Jayasankar, Divya; Hernandez-Serrano, A. I.; Hand, Rachel A.; Stake, Jan; Pickwell‐MacPherson, Emma

doi:10.23919/eumc54642.2022.9924308

Cited by 2 publications

(2 citation statements)

References 11 publications

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“…Due to the challenges associated with obtaining human tissue for THz imaging experimental studies, a couple of studies have explored the development of tissue models, also known as phantoms. The THz imaging of phantoms have been investigated in cancer detection studies including [109], [135], [136], [137], [138], and [139].…”

Section: ) Thz Imaging Of Phantomsmentioning

confidence: 99%

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Gezimati

Singh

2023

IEEE Access

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There is a keen interest in the exploration of new generation emitters and detectors due to advancements in innovation of new materials and device processing technologies which have opened up new frontiers in the Terahertz (THz) spectrum. Therefore, it is necessary to review the developments in THz technology for healthcare applications, their impact, implications and prospects for ongoing research and development. This paper provides a broad overview of the current status and prospects of application of THz imaging and sensing for the healthcare domain. We present current knowledge, identify existing challenges for wide scale clinical adoption of THz systems and prospective opinions to facilitate research and development towards optimized and miniaturized THz systems and biosensors that provide real operational convenience through emerging trends. Firstly, we provide an overview of the THz imaging and sensing techniques that exploit properties of THz generation and detection with emphasis on terahertz time domain spectroscopy (THz-TDS) and THz Metamaterials. The mechanisms of tissue image contrast and the application of THz imaging and sensing for biomedical applications in particular, the cancer detection application is reported. Secondly, an outlook toward the advancements in THz technology in the interface of healthcare 4.0 and its enabling technologies is explored for next generation smart and connected healthcare systems. Third, we identify the merits and existing challenges in THz cancer imaging and sensing and suggest prospective opinions to pave way to ongoing and future research. Further, we discuss the recent advances in THz imaging development and the contribution of near-field techniques based on plasmonic, and resonance based metasurfaces, waveguides etc. for breaking the diffraction limit towards development of THz systems that are convenient for point of care. We bring researchers a roadmap for future research scope.

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Section: ) Thz Imaging Of Phantomsmentioning

confidence: 99%

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Gezimati

Singh

2023

IEEE Access

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“…Thus, we have been conducting research on epidermis‐equivalent phantoms for use in exposure measurements. Although the phantom materials have already been investigated (Truong et al., 2018; Walker et al., 2004), there are still few reports on the spectroscopic evaluation of epidermis‐equivalent phantoms (Jayasankar et al., 2022) in the THz‐frequency region. Therefore, we have evaluated the complex refractive index and reflectance of epidermis‐equivalent phantoms using the THz‐TDSs.…”

Section: Introductionmentioning

confidence: 99%

Spectroscopic Evaluation of Epidermis‐Equivalent Phantom in Terahertz‐Frequency Region

Mizuno,

Yamazaki,

Nagaoka

2024

Radio Science

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The complex refractive index and reflectance of an epidermis‐equivalent phantom were evaluated in the terahertz‐frequency region. The complex refractive indices of the epidermis and the epidermis‐equivalent phantom, made using ultrapure water, mineral oil, glycerin fatty acid ester, and agar, were measured using a terahertz time‐domain spectrometer. The complex refractive indices of the epidermis and the epidermis‐equivalent phantom were in agreement. However, their mean reflectances had a difference of approximately 3%. The difference disappeared on adding surface roughness to the epidermis‐equivalent phantom. Thus, we found that roughness of the surface of the epidermis‐equivalent phantom was required to ensure a match of the reflectance of the phantom with that of the epidermis at frequencies from 0.2 THz to 0.6 THz.

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Investigation of Hydrogel Skin Phantoms Using Terahertz Time-domain Spectroscopy

Cited by 2 publications

References 11 publications

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Spectroscopic Evaluation of Epidermis‐Equivalent Phantom in Terahertz‐Frequency Region

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