Investigation of cross-reactivity between phenobarbital and levetiracetam in children with epilepsy: A prospective, observational multicenter study

Rahimi, Samane; Danaei, Bardia; Nasehi, Mohammad Mehdi; Saket, Sasan; Farahbakhsh, Nazanin; Rajabnejad, Maryam; Taghdiri, Mohammad Mahdi

doi:10.1016/j.ebr.2023.100583

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Methods In Detection Of Ahtds2

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2023

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“…Cross-sensitivity or cross-reactivity occurs when drugs of the same class (often with similar structures) have nearly identical toxicity profiles in the same patients. This possibility justifies avoiding the use of such cross-reacting medicines as much as possible [ 56 , 57 ]. Examples of drug classes that exhibit cross-sensitivity include aromatic anticonvulsants, angiotensin-converting enzyme (ACE) inhibitors, propionate NSAIDs, tricyclic antidepressants (TCAs), erythromycin, phenothiazines, and haloalkane anesthetics [ 56 , 57 ].…”

Section: Methods In Detection Of Ahtdsmentioning

confidence: 99%

“…This possibility justifies avoiding the use of such cross-reacting medicines as much as possible [ 56 , 57 ]. Examples of drug classes that exhibit cross-sensitivity include aromatic anticonvulsants, angiotensin-converting enzyme (ACE) inhibitors, propionate NSAIDs, tricyclic antidepressants (TCAs), erythromycin, phenothiazines, and haloalkane anesthetics [ 56 , 57 ]. Cross-reactivity between drugs and AHTDs can result in either increased or decreased antihypertensive effects.…”

Section: Methods In Detection Of Ahtdsmentioning

confidence: 99%

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