Investigation of COVID-19 By Theoretical Docking of Medicines With Two Proteins

Abstract

This study examined the docking of two inhibition for SARS-Cov-2 virus (or COVID-19) these proteins are (6wtt and 6xa4) with nine pharmaceutical compounds (Aminoglutethimide, 4-Aminosalicylic acid, Felbamate, Hydroflumethiazide, Modafinil, Nepafenac, Oxcarbazepine, and Trichlormethiazide) which are used in the general human's life. These pharmaceuticals have different active groups in the structure conformation like (-NH2) and (-OH). Docking was applied the investigate the interaction between these medicines with the proteins using Molecular Operating Environment software (MOE). The goal of this study was to find a novel drug that docked with some proteins and was regarded to be an effective therapy for COVID-19.