2012
DOI: 10.1007/s11571-012-9214-0
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Investigation of changes in EEG complexity during memory retrieval: the effect of midazolam

Abstract: The aim of this study is applying nonlinear methods to assess changes in brain dynamics in a placebo-controlled study of midazolam-induced amnesia. Subjects injected with saline and midazolam during study, performed old/new recognition memory tests with EEG recording. Based on previous studies, as midazolam causes anterograde amnesia, we expected that midazolam would affect the EEG's degree of complexity. Recurrence quantification analysis, and approximate entropy were used in this assessment. These methods co… Show more

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Cited by 19 publications
(11 citation statements)
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References 66 publications
(56 reference statements)
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“…Anterograde amnesia (forgetting information that is acquired after drug administration) has been demonstrated following administration of midazolam in several studies (5,6,14,20-23). Amnesia seems to be an advantage for patients who want to avoid the memory of an unpleasant experience during dental surgery.…”
Section: Discussionmentioning
confidence: 99%
“…Anterograde amnesia (forgetting information that is acquired after drug administration) has been demonstrated following administration of midazolam in several studies (5,6,14,20-23). Amnesia seems to be an advantage for patients who want to avoid the memory of an unpleasant experience during dental surgery.…”
Section: Discussionmentioning
confidence: 99%
“…Follow-up studies extended the object discrimination task to animals versus inanimate object categories and mammals versus tools, showing that non-face objects could also be correctly categorized (Murphy et al 2008b). Besides the N170 component in ERP responses, Talebi et al (2012) determined that the positive amplitudes of ERP in 300-500 ms were considerably larger for old items than for new. Bigdely-Shamlo et al (2008) detected satellite images containing target objects (i.e., airplanes) using P3 features in ERP recorded during a rapid serial visual presentation.…”
Section: Introductionmentioning
confidence: 99%
“…Measures based on vertical lines, marks state where trapped for some time. This is a typical behavior of laminar states [15][16][17].…”
Section: ) Recurrence Qualification Analysismentioning
confidence: 84%