Investigation of cationic transformations involving 5-ethynyl-4-arylpyrimidines

Shcherbakov, S. V.; Magometov, Artyom Yu.; Vendin, Maksim V; Shcherbakova, Viktoria Yu; Aksenov, Nicolai A.; Аксенов, А. В.; Naji, O.; Rubin, Michael

doi:10.1016/j.tet.2022.132796

Cited by 5 publications

(2 citation statements)

References 29 publications

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“…The column chromatography was performed with Macherey Nagel Silica gel 60 (particle size: 0.063–0.2 mm). The pyrimidines were synthesized by published methods [ 22 , 23 ] and the synthesis of 5-ethynylpyrimidines is described in our recent report [ 24 ]. All other reagents and solvents were purchased from commercial vendors and used as received.…”

Section: Methodsmentioning

confidence: 99%

Annulation of Perimidines with 5-Alkynylpyrimidines en Route to 7-Formyl-1,3-Diazopyrenes

Shcherbakov

Аксенов

Vendin

et al. 2022

IJMS

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Section: Methodsmentioning

confidence: 99%

Annulation of Perimidines with 5-Alkynylpyrimidines en Route to 7-Formyl-1,3-Diazopyrenes

Shcherbakov

Аксенов

Vendin

et al. 2022

IJMS

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“…2022 年, Rubin 等 [82] 报道了仅在三氟甲磺酸存在下, 5-乙炔基-4-芳基嘧啶发生分子内的亲电螺环化/去芳构化反应, 合成了含嘧啶基团的螺环己二烯酮衍生物. Jeganmohan 等 [83] 在三氟乙酸条件下也实现了 2-联苯乙炔衍生物的去芳构化过程.…”

Section: 其他分子内去芳构化反应unclassified

Progress in the Construction of Spirocyclohexadienones via Alkyne-Involving Dearomatization

Liu,

Zhong,

Liao

et al. 2023

Chinese Journal of Organic Chemistry

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Spirocyclohexadienones are not only widely present in bioactive molecules, but also act as key synthetic intermediates for the synthesis of natural products. Owing to the great importance of these compounds, their efficient synthesis has drawn considerable attention from synthetic chemists. In particular, there are many reports about the synthesis of spirocyclohexadienone derivatives via alkyne-involving dearomatization in the past few years. The success of these reactions benefits from the reaction mode: the activation of alkyne π bond by radicals, electrophiles, or metal catalysts under the conditions of photocatalysis, electrocatalysis, or chemical oxidation, and then the subsequent dearomatization process. The advances in electron-deficient, electron-ordinary, and electron-rich alkynes-participated dearomatization of phenolic derivatives to realize the efficient construction of spirocyclohexadienone derivatives in recent five years are systematically summarized. During the discussion, the used triggering ways are subdivided. At last, the prospects of this field are discussed.

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Oxidation of 2-(5-bromo-3,4-dihydropyrimidin-4-yl)phenols, a new approach to the synthesis of benzofuro[3,2-d]pyrimidines

et al. 2023

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Investigation of cationic transformations involving 5-ethynyl-4-arylpyrimidines

Cited by 5 publications

References 29 publications

Annulation of Perimidines with 5-Alkynylpyrimidines en Route to 7-Formyl-1,3-Diazopyrenes

Annulation of Perimidines with 5-Alkynylpyrimidines en Route to 7-Formyl-1,3-Diazopyrenes

Progress in the Construction of Spirocyclohexadienones via Alkyne-Involving Dearomatization

Oxidation of 2-(5-bromo-3,4-dihydropyrimidin-4-yl)phenols, a new approach to the synthesis of benzofuro[3,2-d]pyrimidines

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