Investigation of a Community Outbreak of Diarrhea Associated with Drinking Water in Suburb of Chengdu, China

Abstract

Objectives: To identify the etiology and source after recognition of diarrhea outbreak is associated with drinking water in suburb of Chengdu. Methods: Both unmatched case control and retrospective cohort study were conducted. 131 targets including 56 suspected patients were recruited for case control study, while 463 residents were selected for cohort study. Stool, water and environmental samples were collected for laboratory testing. Results: The proportion of case exposed to well water was 86% in case group compared with 51% in the controls during the epidemic period (OR = 6.14, P < 0.01). Exposing to well water (RR = 3.14, P < 0.01) and the distance between well and river (RR = 2.59, P < 0.01) were at higher risk for diarrheal illness. Nucleic acid of Enteropathogenic E. coli and Enterotoxigenic E. coli was positive in stool and river samples. Conclusions: This outbreak of diarrhea might be caused by several mixed opportunistic pathogens in well water contaminated from the river water.

Antibiotic Use in Agriculture and Its Consequential Resistance in Environmental Sources: Potential Public Health Implications

“…A shigellosis outbreak among 533 students in a rural elementary school in China was investigated, and findings were linked to the presence of Shigella flexneri 2b in untreated well water [ 281 ]. A diarrhoea outbreak in China caused by enteropathogenic and enterotoxigenic E. coli was noted among 131 individuals exposed to well water contaminated by river water [ 282 ]. Between May and August 2010 in Southern Vietnam, Nguyen and co-authors [ 283 ] documented an outbreak of diarrhea that infected seventy-one persons through the consumption of iced tea contaminated with V. cholerae O1, altered El Tor strains.…”

Following WHO Guidelines to Respond to a Water Contamination Outbreak in the Edge of Hamadan, West of Iran

“…This accentuates the pivotal role of epidemiological research in identifying risk factors and implementing targeted control measures to address such outbreaks. Contaminated waterinduced epidemics are particularly prevalent due to the proximity of sewage wells to water wells, as evidenced in previous studies (17,18).…”

Synthesis of a pentasaccharide repeating unit corresponding to the cell wall O-antigen of Escherichia coli O59 using iterative glycosylations in one pot

“…1 Consumptions of the contaminated food and water are the major causes of bacterial infections leading to the diarrheal outbreaks. 2 Among several bacteria responsible for the diarrheal infections, Escherichia coli, Salmonella, Shigella are predominant. 3e5 Even though, E. coli strains exist as commensal organism in the human gastrointestinal flora, they often acquire virulence and cause several infections such as diarrhea, 6 septicemia 7 and urinary tract infections.…”