Investigation of 3D-printed PNIPAM-based constructs for tissue engineering applications: a review

Wu, Kun; Hu, Yanan; Feng, Huiping

doi:10.1007/s10853-023-09125-8

Cited by 1 publication

(1 citation statement)

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“…Studies have shown that 3D printing can simulate complex 3D microenvironments within the body, including the lung, gastrointestinal tract, and vascular system, as well as micro-robotic drug delivery systems. By utilizing materials such as hydrogels [202], poly(N-isopropylacrylamide) (PNI-PAm) [203], 3D printing is also being adapted for drug delivery applications, addressing challenges related to resolution and scalability. As material manufacturing capabilities are integrated into 3D printing technology, the advent of 4D printing systems has emerged.…”

Section: Three-dimensional Printing (3dp) Technologymentioning

confidence: 99%

Novel Drug Delivery Systems: An Important Direction for Drug Innovation Research and Development

Chen,

Yang,

Liu

et al. 2024

Pharmaceutics

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The escalating demand for enhanced therapeutic efficacy and reduced adverse effects in the pharmaceutical domain has catalyzed a new frontier of innovation and research in the field of pharmacy: novel drug delivery systems. These systems are designed to address the limitations of conventional drug administration, such as abbreviated half-life, inadequate targeting, low solubility, and bioavailability. As the disciplines of pharmacy, materials science, and biomedicine continue to advance and converge, the development of efficient and safe drug delivery systems, including biopharmaceutical formulations, has garnered significant attention both domestically and internationally. This article presents an overview of the latest advancements in drug delivery systems, categorized into four primary areas: carrier-based and coupling-based targeted drug delivery systems, intelligent drug delivery systems, and drug delivery devices, based on their main objectives and methodologies. Additionally, it critically analyzes the technological bottlenecks, current research challenges, and future trends in the application of novel drug delivery systems.

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Section: Three-dimensional Printing (3dp) Technologymentioning

confidence: 99%