Investigating the sociodemographic and behavioural factors associated with hepatitis C virus testing amongst people who inject drugs in England, Wales and Northern Ireland: A quantitative cross-sectional analysis

Yuan, Jingjie; Croxford, Sara; Viviani, Laura; Emanuel, Eva; Phipps, Emily; Desai, Monica

doi:10.1016/j.drugpo.2022.103821

Cited by 3 publications

(1 citation statement)

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“…This increases risk of viral infection and respiratory harm among a marginalised underserved population [15]. Crack injection is associated with elevated bloodborne virus (HCV, HIV) and bacterial infection risk [16], given increased injection frequency compared to opioid use [17].…”

Section: Introductionmentioning

confidence: 99%

Crack Cocaine Use and Mortality Risk: A Follow-Up Study on 178 Individuals in Drug Treatment for Crack Cocaine Problems

Pavarin

2024

ebph

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Background: In Europe, crack cocaine use is mainly observed in vulnerable and marginalized groups, many of whom have other substance use problems, including heroin-related problems. Objectives: To examine mortality risk and causes of death in a cohort of crack users.Methods: We performed a follow-up study to assess mortality in a cohort of patients who entered drug treatment for crack cocaine problems in the metropolitan area of Bologna (Northern Italy) from 1992 to 2020.Results: Most of participants were polydrug users, 75% reported concomitant heroin, 55% cocaine and 24% alcohol use; 43% have injected a substance. Mortality was six times higher than in the general population, and overdose and infectious diseases were among the leading causes of death.Conclusions: Longitudinal epidemiological studies are needed to systematically assess the health outcomes of crack cocaine use.

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Section: Introductionmentioning

confidence: 99%

Crack Cocaine Use and Mortality Risk: A Follow-Up Study on 178 Individuals in Drug Treatment for Crack Cocaine Problems

Pavarin

2024

ebph

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Has the HCV cascade of care changed among people who inject drugs in England since the introduction of direct-acting antivirals?

Gliddon,

Ward,

Heinsbroek

et al. 2024

International Journal of Drug Policy

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Systematic review and meta-analysis to estimate the burden of non-fatal and fatal overdose among people who inject drugs living in the U.S. and comparator countries: 2010 – 2023

Shealey,

Hall,

Pigott

et al. 2024

Preprint

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BackgroundPeople who inject drugs (PWID) have high risk for overdose, but there are no current estimates of overdose rates in this population. We estimated the rates of non-fatal and fatal overdose among PWID living in the U.S. and comparator countries (Canada, Mexico, United Kingdom, Australia), and ratios of non-fatal to fatal overdose, using literature published 01/01/2010 – 09/29/2023.MethodsPubMed, PsychInfo, Embase, and ProQuest databases were systematically searched to identify publications reporting prevalence or rates of recent (past 12 months) non- fatal and fatal overdose among PWID. Non-fatal and fatal overdose rates were meta-analyzed using random effects models. Risk of bias was assessed using an adapted quality assessment tool, and heterogeneity was explored using sensitivity analyses.ResultsOur review included 143 records, with 58 contributing unique data to the meta- analysis. Non-fatal and fatal overdose rates among PWID in the U.S. were 32.9 per 100 person- years (PY) (95% CI: 26.4 – 40.9; n=28) and 1.7 per 100 PY (95% CI: 0.9 – 3.2; n=4), respectively. Limiting the analysis to data collected after 2016 yielded a non-fatal rate of 41.0 per 100 PY (95% CI: 32.1 – 52.5; n=16) and a fatal rate of 2.5 per 100 PY (95% CI: 1.4 – 4.3; n=2) in the U.S. An estimated 5% of overdoses among PWID in the U.S. result in death. Among the analyzed countries, Australia had the lowest non-fatal and fatal overdose rates and the largest ratio of non-fatal to fatal overdose.ConclusionFindings demonstrate substantial burden of non-fatal and fatal overdose among PWID in the U.S. and comparator countries. Scale-up of interventions that prevent overdose mortality and investments in PWID health research are urgently needed.

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Investigating the sociodemographic and behavioural factors associated with hepatitis C virus testing amongst people who inject drugs in England, Wales and Northern Ireland: A quantitative cross-sectional analysis

Cited by 3 publications

References 80 publications

Crack Cocaine Use and Mortality Risk: A Follow-Up Study on 178 Individuals in Drug Treatment for Crack Cocaine Problems

Crack Cocaine Use and Mortality Risk: A Follow-Up Study on 178 Individuals in Drug Treatment for Crack Cocaine Problems

Has the HCV cascade of care changed among people who inject drugs in England since the introduction of direct-acting antivirals?

Systematic review and meta-analysis to estimate the burden of non-fatal and fatal overdose among people who inject drugs living in the U.S. and comparator countries: 2010 – 2023

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