Investigating the relationship between lifestyle factors, family history, and diabetes mellitus in non-diabetic visitors to primary care centers

Abdulaziz Alrashed, Fahad; Ahmad, Tauseef; Almurdi, Muneera M.; Alqahtani, Abdulfattah S.; Alamam, Dalyah M.; Alsubiheen, Abdulrahman M.

doi:10.1016/j.sjbs.2023.103777

Cited by 2 publications

(5 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In our study, 62.2% of participants reported a family history of diabetes. There is established literature suggesting a genetic predisposition to T2DM [ 21 , 32 , 33 ]. There was a statistically significant correlation ( p = 0.004) between individuals with a family history of diabetes and the prevalence of diabetes within this group, with 28.8% affected.…”

Section: Discussionmentioning

confidence: 99%

“…It represents a global health challenge, and its prevalence has been steadily rising, notably in Saudi Arabia. The impact of T2DM is multifaceted, and recent research has begun to explore how sex and family history may influence not only the prevalence of T2DM but also its comorbidity patterns and associated determinants among clinical patients in Saudi Arabia [ 19 – 21 ].…”

Section: Introductionmentioning

confidence: 99%

“…These shifts have contributed to an elevated risk of developing T2DM among the Saudi population [ 1 , 3 , 22 ]. Furthermore, family history of T2DM and genetic predisposition were acknowledged risk factors that underscore the importance of understanding the influence of family history on the prevalence and comorbidity of T2DM [ 21 , 23 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Exploring determinants of sex and family history-based disparity in type 2 diabetes mellitus prevalence among clinical patients

Alrashed,

Iqbal,

Alsubiheen

et al. 2024

BMC Public Health

Self Cite

View full text Add to dashboard Cite

Background Type 2 diabetes mellitus represents a multifaceted disorder characterized by intricate pathophysiological mechanisms, encompassing diminished insulin secretion, augmented hepatic glucose production, and heightened insulin resistance. This study aims to assess the sex (Male and Female only) and family history-based differences in the prevalence of T2DM and explore the determinants contributing to this disparity among clinical patients. Subjects and methods The study encompassed a diverse pool of clinical patients, encompassing both individuals with diabetes and those without the condition, who had previously sought medical attention for clinical checkups at healthcare centers. The collected data included essential parameters such as blood pressure, weight, height, smoking habits, educational background, and physical activity levels. To ensure methodological rigor and data accuracy, blood pressure measurements adhered to the stringent guidelines set forth by the World Health Organization. Results Participants of the present study reported diabetes, among which notable findings emerged regarding health indicators. It was observed that the prevalence of high blood pressure, obesity, and high blood cholesterol exhibited a statistically significant increase among the female participants, underscoring the sex-based disparities in these health parameters. The male population aged 60 or older, the presence of a family history of DM accentuated this risk, resulting in a striking 3.1 times higher prevalence compared to females, who exhibited a 2.4 times higher risk (OR = 2.4, p = 0.0008). This intriguing relationship between diabetes and cholesterol levels was not limited to sex. Both male (OR = 2.47) and female (OR = 2.1) diabetes patients displayed highly significant associations with cholesterol levels. The risk of T2DM was significantly associated with triglycerides in both sexes (1.58 times higher in males, and 1.71 times higher in females). Conclusions The significance of hypertension as a comorbidity in T2DM, highlighting sex-specific associations and the potential impact of a family history of diabetes on blood pressure. Our findings emphasize the importance of considering lipid profiles, obesity, and their sex-specific associations when assessing and managing diabetes risk. Comprehensive diabetes care should include strategies for lipid control, weight management, and cardiovascular risk reduction, tailored to the individual’s sex and specific risk profile.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Exploring determinants of sex and family history-based disparity in type 2 diabetes mellitus prevalence among clinical patients

Alrashed,

Iqbal,

Alsubiheen

et al. 2024

BMC Public Health

Self Cite

View full text Add to dashboard Cite

show abstract

“…There was a strong association between patients with T2DM and those who have a family history of diabetes [10]. The prevalence of T2DM related to family history, namely father (25.8%), mother (14.5%), and both father and mother (40.3%), and variable mothers significantly associated with the incidence of T2DM at p<0.05.…”

Section: Family Historymentioning

confidence: 90%

“…Estrogen can affect insulin sensitivity and blood sugar metabolism. Apart from that, it is also influenced by diet, lack of physical activity, and genetic factors [10]. Results of the study showed the prevalence of T2DM tends to increase with age and occurs relatively higher for 46+ years (69.4%), and women living with T2DM reached 74.2%.…”

Section: Prevalence Of Participants Living With T2dmmentioning

confidence: 91%

Analysis of Associated Factors Contributing to Type 2 Diabetes Mellitus in the Coastal Community of Bahari Village, Southeast Sulawesi, Indonesia: A Cross-Sectional Study

Muhammadong,

Yuyun,

Muriman

et al. 2024

TOPHJ

View full text Add to dashboard Cite

Background Type 2 diabetes mellitus (T2DM) has become a major lifestyle disease that threatens communities in the world. The lifestyles of undiagnosed T2DM are a major issue in Indonesia. Objective This study aims to analyze the contribution of associated factors to T2DM in Bahari Village. Methods The study was conducted by cross-sectional study. Respondents included 113 men and 157 women were established through simple randomized sampling from March to May 2023. Data analysis using chi-square and logistic regression at p<0.05 using SPSS 25. Results The prevalence of T2DM for women (74.2%), 45-65 years (90.9%), no education (58.7%), overweight (38.2%), heavy drinking sweet tea/coffee (77.5%), never physical activity (87.1%), diabetic father and mother (40.3%), and father’s OR 1.42 (CI 95%:0.73-2.75), significantly associated with T2DM. Gender, age, education, BMI, and occupation simultaneously influence (72.7%), and age partially affects T2DM. Discussion Decreased insulin sensitivity and increased risk of developing diabetes can be influenced by various factors, such as genetics, lifestyle, physical activity, and the environment, either partially or simultaneously. Conclusion The respondents' advanced age, obesity, lack of education, preference for sweet foods, and inactivity all contributed to their type 2 diabetes. These coastal communities need to make lifestyle changes to reduce the burden of diabetes. Classification Epidemiology; Environmental Health; Science of Nutrition MeSH.

show abstract

Investigating the relationship between lifestyle factors, family history, and diabetes mellitus in non-diabetic visitors to primary care centers

Cited by 2 publications

References 46 publications

Exploring determinants of sex and family history-based disparity in type 2 diabetes mellitus prevalence among clinical patients

Exploring determinants of sex and family history-based disparity in type 2 diabetes mellitus prevalence among clinical patients

Analysis of Associated Factors Contributing to Type 2 Diabetes Mellitus in the Coastal Community of Bahari Village, Southeast Sulawesi, Indonesia: A Cross-Sectional Study

Contact Info

Product

Resources

About