Investigating the metal-enhanced fluorescence on fluorescein by silica core-shell gold nanoparticles using time-resolved fluorescence spectroscopy

Liu, Yiting; Luo, Xue-Feng; Lee, Yin‐Yu; Chen, I‐Chia

doi:10.1016/j.dyepig.2021.109263

Cited by 12 publications

(13 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Accordingly, the fluorescence emission displayed biexponential behavior of a rise component lifetime 300 ps and a decay component 3.48 ns in basic solution and 220 ps and 3.29 ns in neutral water solution. Similar results were reported by Liu et al [ 19 ] The short rise component corresponded to the process of reaching equilibrium between F 2− and HF − in the excited states and the long component to the fluorescence decay of both species in their S 1 states. FITC embedded in silica thin layer binding to silica nanoballs had emission time constant of 0.065 ns for the rise and 2.95 ns for the decay and a quantum yield of 0.49.…”

Section: Resultssupporting

confidence: 90%

“…These measured fluorescence intensities I fluo excited at 532 nm were corrected over the scattering loss due to the large particle size of AuNC@SiO 2 @FITC. [ 9,19,25 ] The values of EF were 1.73/1.71, 1.57/1.51, 1.25/1.22, 1.24/1.13, and 1.03/1.01 for the neutral/basic solution for L S from 12 to 40 nm. These values are listed in Table 1.…”

Section: Resultsmentioning

confidence: 97%

“…The values are listed in Table 1 in comparison with EF of nanocubes and nanospheres (70 nm diameter). [ 19 ] Comparing the EF values of the same L s , the EF of triangles was slightly better than those in cubes and spheres although the spectral overlap is the worst.…”

Section: Resultsmentioning

confidence: 99%

“…About 1 ml of AuNT@SiO 2 solution (absorbance 3/cm) was mixed with 50 μl of the fluorescein–APTES solution, 450 μl of 9 mM TEOS, and 180 μl of NH 4 OH for 20 hr reaction in the dark and at room temperature to produce AuNT@SiO 2 @FITC. [ 18,19 ]…”

Section: Methodsmentioning

confidence: 99%

“…[ 17 ] FITC can react with the amino group in silica to be fixed onto the surfaces of silica shell. [ 18,19 ] Silica is an inert material but with mesopores, and fluorophores can be embedded onto the outermost pores. Using this synthetic method of FITC–silica mixed material prohibited dye molecules' diffusion into the silica shell to reach a fixed distance between fluorophore and metal surface.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Investigating metal‐enhanced fluorescence effect on fluorescein by gold nanotriangles and nanocubes using time‐resolved fluorescence spectroscopy

Luo

Lai

Lee

et al. 2021

J Chinese Chemical Soc

View full text Add to dashboard Cite

Gold nanotriangles (AuNTs) and nanocubes (NCs) coated with silica shell and fluorescein were synthesized to study the effects of metal‐enhanced fluorescence. The interaction between gold nanoparticles (GNPs) and fluorescein with silica shells of different thicknesses as spacers was investigated by using time‐resolved fluorescence spectroscopy. From the biexponential decay of fluorescence of fluorophore and the kinetic mechanism for the interaction, we obtained the rate constants of energy transfer processes. Both energy transfer rates from fluorophore to the bright and dark modes of gold nanoparticles decreased with distance d (= silica thickness) with a dependence ∝ d−n and n ≈ 2. The rate constant of nanosurface energy transfer kNEST, considering dipolar interaction between fluorophore and metal surface, has an estimated value 1.7 times slower at d = 9 nm and about four times slower at 25 nm than the obtained rate constant for energy transfer from fluorophore to GNP dipolar mode in the AuNT system. For the AuNC system, the rate constants are greater than the AuNT system because of better spectral overlap between emission of fluorescein and surface plasmon resonance.

show abstract

Section: Resultssupporting

confidence: 90%

Section: Resultsmentioning

confidence: 97%

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Investigating metal‐enhanced fluorescence effect on fluorescein by gold nanotriangles and nanocubes using time‐resolved fluorescence spectroscopy

Luo

Lai

Lee

et al. 2021

J Chinese Chemical Soc

View full text Add to dashboard Cite

show abstract

Ultrahigh Raman‐Fluorescence Dual‐Enhancement in Nanogaps of Silver‐Coated Gold Nanopetals

Fang

Deng

et al. 2023

Advanced Optical Materials

View full text Add to dashboard Cite

Raman-fluorescence dual-mode enhanced nanoparticles have enormous potential for bioimaging with combined advantages of sensitivity and speed. This is primarily achieved through a trade-off between fluorescence quenching and electromagnetic (EM) enhancement on the plasmonic metal surface, as demonstrated in previous research. A strategy that can minimize EM-field attenuation and temporal photobleaching would be highly desirable. In this study, a novel approach using Raman-fluorescence enhanced dual-mode nanoparticles with the near-infrared fluorescence reporter IR780 directly embedded in the ultra-high EM fields between gold (Au) nanopetals of various morphology and a silver (Ag) coating without a spacer is presented. The results show these nanoparticles to be single-nanoparticle Raman sensitive and that they can generate a fluorescence enhancement factor as high as 1113 experimentally and 2000 by numerical simulation. The random morphology of the nanopetals supports broadband resonances for both fluorescence excitation and emission, resulting in nanowatt detectability, the dual-mode photostability of more than 30 min under continuous laser irradiation, and a long shelf life, making them promising for wide applications in bioimaging with ultra-brightness, low laser power, and long-duration monitoring. In summary, they represent a novel strategy for high-performance Raman-fluorescence enhancement dual-mode nanotags.

show abstract

Hydrogels of Alginate Derivative‐Encased Nanodots Featuring Carbon‐Coated Manganese Ferrite Cores with Gold Shells to Offer Antiangiogenesis with Multimodal Imaging‐Based Theranostics

Gowtham,

Girigoswami,

Prabhu

et al. 2024

Advanced Therapeutics

View full text Add to dashboard Cite

The investigation seeks to develop gold‐shelled carbon‐coated manganese ferrite nanodots enclosed within oxidized alginate polymeric hydrogels to improve encapsulation efficiency, biocompatibility, and multimodal imaging capabilities. These engineered particles, MNF@C‐Au@OSA, are crafted through a hydrothermal synthesis, succeeded by the application of gold nanoparticle shelling and subsequent encapsulation within hydrogels derived from synthesized alginate derivatives, enhancing their overall appeal. Diverse characterization methodologies are employed in order to validate the multiple steps of the synthesis process. The resulting engineered nanoparticles exhibit dual‐mode (T1 and T2) MRI contrast capabilities and compatibility with CT and fluorescence‐based imaging. To illustrate minimal toxicity, A375 cell lines are utilized for in vitro testing, whereas zebrafish embryos are employed for in vivo assessments. A Chorioallantoic Membrane Model (CAM) is used to establish the antiangiogenic characteristics of MNF@C‐Au@OSA, which is confirmed by histopathological observations. Taking these studies together, one can conclude that the engineered MNF@C‐Au@OSA possesses multimodal imaging capabilities and has demonstrated antiangiogenic properties, thereby establishing them as potential theranostic agents.This article is protected by copyright. All rights reserved

show abstract

Investigating the metal-enhanced fluorescence on fluorescein by silica core-shell gold nanoparticles using time-resolved fluorescence spectroscopy

Cited by 12 publications

References 51 publications

Investigating metal‐enhanced fluorescence effect on fluorescein by gold nanotriangles and nanocubes using time‐resolved fluorescence spectroscopy

Investigating metal‐enhanced fluorescence effect on fluorescein by gold nanotriangles and nanocubes using time‐resolved fluorescence spectroscopy

Ultrahigh Raman‐Fluorescence Dual‐Enhancement in Nanogaps of Silver‐Coated Gold Nanopetals

Hydrogels of Alginate Derivative‐Encased Nanodots Featuring Carbon‐Coated Manganese Ferrite Cores with Gold Shells to Offer Antiangiogenesis with Multimodal Imaging‐Based Theranostics

Contact Info

Product

Resources

About