Investigating the Influence of Vaccine Literacy, Vaccine Perception and Vaccine Hesitancy on Israeli Parents’ Acceptance of the COVID-19 Vaccine for Their Children: A Cross-Sectional Study

Abstract

Vaccination is currently the most effective strategy for combating COVID-19. COVID-19 vaccines were introduced to the adult population in Israel in early December 2020 and have been available for children aged 12–15 since June 2021. Our study aimed at assessing the influence of vaccine literacy, perception, hesitancy, and behavior on Israeli parents’ intentions to have their children vaccinated. Using an anonymous online questionnaire, we recruited 520 parents; 70.4% of the parents indicated that they would get their children vaccinated. The participants’ COVID-19 vaccination status was the only socio-demographic factor significantly associated with COVID-19 vaccination acceptability (OR = 32.89; 95%CI = [13.11, 82.54]). The most common sources of information regarding the COVID-19 vaccine were health-care providers and the Internet. Parents who intend to vaccinate their children had higher mean levels of vaccine literacy (2.99 ± 0.47 vs. 3.07 ± 0.44 respectively, p = 0.06), more positive perception of the vaccine (mean scores of 2.26 ± 0.75 vs. 3.44 ± 0.68 respectively, p < 0.001), and lower perceived vaccine hesitancy (7.53 ± 2.37 vs. 4.68 ± 2.71 respectively, p < 0.001) than parents who do not intend to do so. Vaccine behavior was measured using the 5C model of psychological antecedents. All 5C components were significantly correlated with parents’ willingness to vaccinate their children. Understanding of parents’ willingness to have their children receive the COVID-19 vaccine and the barriers to and facilitators of the vaccination is crucial, as vaccination of children aged 5–11 has recently been approved by the FDA. Providing the population with reliable information regarding the COVID-19 vaccine is an important measure in the attempt to increase COVID-19 vaccine acceptance.

Determinants of COVID-19 Vaccine Uptake in Adolescents 12–17 Years Old: Examining Pediatric Vaccine Hesitancy Among Racially Diverse Parents in the United States

“…Among parents who themselves were vaccinated, the unadjusted odds of vaccine uptake for their older child were 14 times higher than unvaccinated parents. Our findings are consistent with previous research reporting that vaccinated parents are more likely than unvaccinated parents to accept the vaccine for their children ( 6 , 8 – 10 , 12 , 16 , 17 , 19 , 21 , 22 ). Further, our data point to the influence of one's larger social context on vaccine acceptance.…”

Role of literacy, fear and hesitancy on acceptance of COVID-19 vaccine among village health volunteers in Thailand

“…A previous study of physicians in a university-based teaching hospital in Thailand found that better VL was inversely related to VH (aOR 0.34; 95% CI 0.13-0.9; p = 0.029) [22]. Parents with higher VL preferred to vaccinate their children compared to those with lower VL [29]. This is implying the role of VL in reducing VH and increasing AV.…”

Willingness, refusal and influential factors of parents to vaccinate their children against the COVID-19: A systematic review and meta-analysis

“… Yes [Y], unsure [U], no [N] Yes: 70 Unsure: NR No: NR ( Evans et al, 2021 ) If a COVID-19 vaccine is available, will you vaccinate for your child? Yes [Y], unsure [U], no [N] Yes: 48 Unsure: 38 No: 14 ( Gendler and Ofri, 2021 ) If a vaccine against COVID-19 is available, how likely would you be to get your children vaccinated? Very likely [Y], somewhat likely [Y], somewhat unlikely [N], definitely not [N] Yes: 70.4 No:29.6 ( Humble et al, 2021 ) If a safe and effective COVID-19 vaccine is available, I will get my child/children vaccinated Strongly agree [Y], agree [Y], neutral [U], disagree [N], strongly disagree [N] Yes: 63.1 Unsure: NR No: NR ( Kezhong et al, 2021 ) If a COVID-19 vaccine is available, will you vaccinate for your child?…”