Investigating the importance of selected surface-exposed loops in HpuB for hemoglobin binding and utilization by
Neisseria gonorrhoeae
Olivia A. Awate,
Dixon Ng,
Julie L. Stoudenmire
et al.
Abstract:Neisseria gonorrhoeae
is the etiological agent of the sexually transmitted infection gonorrhea. The pathogen is a global health challenge since no protective immunity results from infection, and far fewer treatment options are available with increasing antimicrobial resistance. With no efficacious vaccines, researchers are exploring new targets for vaccine development and innovative therapeutics. The outer membrane TonB-dependent transporters (TdTs) produced by
N. gonorrhoeae
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