Investigating the Expression of Genes Involved in Apoptosis and Mutation in Ovarian Cancer Cell Line and Possible Hepatotoxicity in Rats Induced by New Green Synthesized Ag-NPs
Abstract:Silver nanoparticles (Ag-NPs) can enter tumor cells through endocytosis and transfer to mitochondria, then disrupt mitochondrial function, damage deoxyribonucleic acid (DNA), and finally lead to cell death and apoptosis. As the Ag-NPs synthesized by Moringa peregrina leaf extract contain biomolecules such as flavonoids and terpenoids, they may suppress cancer by disrupting the flow of autophagy and inhibiting the differentiation of cancer cells, especially in apoptosisresistant cancer cells. Accordingly, the 3… Show more
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