Investigating the Cellular and Metabolic Responses of World-Class Canoeists Training: A Sportomics Approach

Abstract

(1) Background: We have been using the Sportomics approach to evaluate biochemical and hematological changes in response to exercise. The aim of this study was to evaluate the metabolic and hematologic responses of world-class canoeists during a training session; (2) Methods: Blood samples were taken at different points and analyzed for their hematological properties, activities of selected enzymes, hormones, and metabolites; (3) Results: Muscle stress biomarkers were elevated in response to exercise which correlated with modifications in the profile of white blood cells, where a leukocyte rise was observed after the canoe session. These results were accompanied by an increase in other exercise intensity parameters such as lactatemia and ammonemia. Adrenocorticotropic hormone and cortisol increased during the exercise sessions. The acute rise in both erythrocytes and white blood profile were probably due to muscle cell damage, rather than hepatocyte integrity impairment; (4) Conclusion: The cellular and metabolic responses found here, together with effective nutrition support, are crucial to understanding the effects of exercise in order to assist in the creation of new training and recovery planning. Also we show that Sportomics is a primal tool for training management and performance improvement, as well as to the understanding of metabolic response to exercise.

Physiological extremes of the human blood metabolome: A metabolomics analysis of highly glycolytic, oxidative, and anabolic athletes

“…While short-term metabolite changes after one exercise session in athletes were reported (Al-Khelaifi et al, 2018, 2019Breit et al, 2015;Coelho et al, 2016;Hall et al, 2016;Howe et al, 2018), no study showed how years of metabolic adaptation to endurance, resistance, or sprint training affect metabolite changes to the same acute exercise.…”

Hematological parameters in champion of Brazilian jiu‐jitsu paradesport: Case study

“…This fact should be considered when prescribing physical training strategies, which should be based on parameters presented by specific studies. In this regard, studies with sports methods have emerged in recent decades as an ideal strategy to study the interactions between exercise, the immune system, and metabolism via cellular adaptations (Bassini-cameron, Bottino, Bittar, Veiga, & Cameron, 2007;Bessa et al, 2008;Coelho et al, 2016).…”

Molecular Portrait of an Athlete

“…Taking the scientific achievements, and available sports infrastructure into account, it is necessary to improve the recommendations made to young athletes for the early detection of a predisposition to engage in specific sports by using physiological, medico-biochemical, and molecular genetic methods. Today, the global scientific community is actively working to identify the endogenous molecular factors and processes that can act as personalized predictors of athletic performance [10][11][12].…”