Investigating mechanosensitive channels activation in concert with the mechanical properties of red blood cells
Nicoletta Braidotti,
Catalin Dacian Ciubotaru,
Davide Rizzo
et al.
Abstract:The activity of the mechanosensitive Ca2+ permeable channels expressed in the membrane of the red blood cells (RBC) is determined both by the mechanical stimuli and the mechanical properties of the cell. Therefore, it is of most importance to correlate the triggering stimulus with the mechanical properties. In this paper, we propose an approach to determine the activation pressure of the mechanosensitive channels and concomitantly evaluate cell mechanical properties as Young’s Modulus, membrane tension and vis… Show more
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