Investigating genetic and environmental contributions to adolescent externalizing behavior in a collectivistic culture: a multi-informant twin study

Chen, Jie; Yu, Jing; Zhang, J.; Li, X.; McGue, Matt

doi:10.1017/s0033291714003109

Cited by 22 publications

(14 citation statements)

References 33 publications

(39 reference statements)

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“…Our univariate analyses similarly demonstrated that our heritability values are similar to those of previous studies, especially for RB and AGG (Chen, Yu, Zhang, Li, & McGue, 2015;Porsch et al, 2016). For sleep duration, our estimate of genetic influence was on the higher end of the wide span of heritability estimates for children found in the literature, where values from .31 to .71 have been reported (Brescianini et al, 2011;Gregory et al, 2006).…”

Section: Discussionsupporting

confidence: 89%

Children Sleep and Antisocial Behavior: Differential Association of Sleep with Aggression and Rule-Breaking

Madrid‐Valero

Ordoñana

Klump

et al. 2018

J Abnorm Child Psychol

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There is a strong relationship between sleep and behavioral problems. These findings are often interpreted via environmental explanations, such that poor sleep directly exacerbates or causes symptoms of aggression and behavior problems. However, there are other possible explanations, such that the genes predicting poor sleep also predict aggression or rule-breaking. The current study sought to elucidate the origin of this relationship. The sample was composed of 1,030 twin pairs (426 monozygotic and 604 dizygotic). The sample was 51.3% male with a mean age of 8.06 years (range 6-11.96; SD=1.45). Aggression, rule-breaking and sleep were assessed through the Child Behavior Checklist (CBCL). We fitted bivariate Cholesky genetic models to the data, decomposing the variance within, and the covariance among, aggression, rule-breaking, and sleep functioning into their genetic and environmental components. Genetic correlations between all sleep variables and aggression were significant and moderate to large in magnitude, but mostly small and non-significant between sleep and rule-breaking. We did not find evidence of a causal or environmental relationship between the majority of sleep variables and aggression, but rather clear evidence of genetic pleiotropy. However, the pattern of associations between rule-breaking and sleep measures was less consistent. Aggression and rule-breaking appear to be differentially associated with sleep.

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Section: Discussionsupporting

confidence: 89%

Children Sleep and Antisocial Behavior: Differential Association of Sleep with Aggression and Rule-Breaking

Madrid‐Valero

Ordoñana

Klump

et al. 2018

J Abnorm Child Psychol

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“…Moreover, the need for social desirability may impede participants from disclosing their impulsive dispositions (detected with FS), which are typically associated with externalizing behaviors (54). This outcome could be more apparent in a collectivistic culture, which encourages social affiliation and leads to lower acceptability of externalizing behaviors (55). We strongly recommend that future studies examine the wording of the Fun Seeking subscale and other problematic items.…”

Section: Discussionmentioning

confidence: 99%

Psychopathological Correlates and Emotion Regulation as Mediators of Approach and Avoidance Motivation in a Chinese Military Sample

et al. 2019

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Background: Approach and avoidance motivation have been thoroughly studied in common mental disorders, which are prevalent in the military context. Approach/avoidance motivational dispositions underlie emotion responses and are thought to influence emotion dysregulation. However, studies on the mediating role of emotion regulation (ER) between motivational dispositions and mental disorders have been insufficient. We examined the psychopathological correlates of motivational dispositions and explored the mediating role of ER. Methods: The Behavioral Inhibition System and Behavioral Activation System (BIS/BAS) scales and measures of mood disorders (depression, anxiety, OCD, and PTSD) were administered to a nonclinical sample of 3,146 Chinese military service members. The Emotion Regulation Questionnaire for Armymen (ERQ-A) (Chinese version) was used to measure ER styles. We examined the reliability and construct validity of the BIS/BAS scales. Approach/avoidance motivations were correlated with symptoms of mood disorders. Mediation analysis was conducted to confirm the mediating role of ER between motivation and mood disorders. Results: The results showed acceptable internal reliability and construct validity of the BIS/BAS scales. Gender (female), family status (single-parent family), and social relationships (having fewer good friends) were significant predictors of high BIS sensitivity. More years of education, an older age, being an only child and being in a single-parent family all significantly predicted high BAS sensitivity. The BIS/BAS scales were predictive of various DSM-V-based mental disorders (depression, anxiety, OCD, and PTSD). Immersion exacerbated the impact of BAS/BIS sensitivities on depressive/PTSD symptoms, while reinterpretation and talking out alleviated the impact of BAS/BIS sensitivities on these symptoms. Conclusions: Motivational dispositions have an impact on mood symptoms under specific conditions. ER strategies (immersion, reinterpretation, and talking out) were shown to be partial mediators between approach/avoidance motivation and mood disorders. These findings highlight the importance of ER in altering the impact of motivational dispositions on mood disorders and as a promising target of psychotherapies.

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“…Proactive aggression showed slightly higher heritability estimates (32–48%) than reactive aggression (20–43%) [Baker et al, ; Tuvblad et al, ]. Highest, but strongly culturally variable, heritability estimates (29–68%) were obtained for the aggression subscale of the CBCL [Burt and Klump, ; Chen et al, ], which does not differentiate between reactive and proactive forms of aggression, and contains several items on physical aggression. The latter also shows relatively high heritability when assessed by other scales (38–60%) [Yeh et al, ; Lacourse et al, ].…”

Section: Methodsmentioning

confidence: 99%

The neurobiological basis of human aggression: A review on genetic and epigenetic mechanisms

Waltes

Chiocchetti

Freitag

2015

American J of Med Genetics Pt B

142

105

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Aggression is an evolutionary conserved behavior present in most species including humans. Inadequate aggression can lead to long-term detrimental personal and societal effects. Here, we differentiate between proactive and reactive forms of aggression and review the genetic determinants of it. Heritability estimates of aggression in general vary between studies due to differing assessment instruments for aggressive behavior (AB) as well as age and gender of study participants. In addition, especially non-shared environmental factors shape AB. Current hypotheses suggest that environmental effects such as early life stress or chronic psychosocial risk factors (e.g., maltreatment) and variation in genes related to neuroendocrine, dopaminergic as well as serotonergic systems increase the risk to develop AB. In this review, we summarize the current knowledge of the genetics of human aggression based on twin studies, genetic association studies, animal models, and epigenetic analyses with the aim to differentiate between mechanisms associated with proactive or reactive aggression. We hypothesize that from a genetic perspective, the aminergic systems are likely to regulate both reactive and proactive aggression, whereas the endocrine pathways seem to be more involved in regulation of reactive aggression through modulation of impulsivity. Epigenetic studies on aggression have associated non-genetic risk factors with modifications of the stress response and the immune system. Finally, we point to the urgent need for further genome-wide analyses and the integration of genetic and epigenetic information to understand individual differences in reactive and proactive AB.

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Investigating genetic and environmental contributions to adolescent externalizing behavior in a collectivistic culture: a multi-informant twin study

Cited by 22 publications

References 33 publications

Children Sleep and Antisocial Behavior: Differential Association of Sleep with Aggression and Rule-Breaking

Children Sleep and Antisocial Behavior: Differential Association of Sleep with Aggression and Rule-Breaking

Psychopathological Correlates and Emotion Regulation as Mediators of Approach and Avoidance Motivation in a Chinese Military Sample

The neurobiological basis of human aggression: A review on genetic and epigenetic mechanisms

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