Investigating emerging infectious diseases

Abubakar, Ibrahim Ahmad; Rangaka, Molebogeng X; Lipman, Marc

doi:10.1093/med/9780198719830.003.0006

Cited by 3 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Transmission dynamic models are tools that help scientists or researchers understand the complex interaction between hosts and pathogens. These models are used to study how a system behaves and responds to interventions, 11,19 for instance studying whether the prevalence of an infection increases or decreases in the absence of intervention, and also studying the fraction of population that needs to be immunized to prevent the pathogen from causing an epidemic. 10 Infectious diseases transmission dynamic models are also used to better understand the system itself -for example, understanding whether the previous infection provides a protection from re-infection or not; or understanding and identifying the number of new cases that depend on the proportion of asymptomatic infectious individuals.…”

Section: Infectious Diseases Transmission Dynamic Modelsmentioning

confidence: 99%

“…10 Infectious diseases transmission dynamic models are also used to better understand the system itself -for example, understanding whether the previous infection provides a protection from re-infection or not; or understanding and identifying the number of new cases that depend on the proportion of asymptomatic infectious individuals. 12,19 https://doi.org/10.2147/IDR.S403133…”

Section: Infectious Diseases Transmission Dynamic Modelsmentioning

confidence: 99%

“…20 A "susceptible-exposed-infectious-recovered (SEIR)" model is another example of an infectious diseases transmission dynamic model that is appropriate for a pathogen with a period of latency. 19,21 HCV Transmission Dynamic Model Among PWID Constructing a transmission model for HCV is very important in order to understand the transmission dynamics and prevalence of HCV infection as well as to predict the trend of the disease and to search for a prevention and control mechanism. 22 Basic susceptible-infected formulations with a variety of modeling approaches including stochastic individual-based and deterministic compartmental, HCV-mono-infection or HIV/HCV joint co-infection were used to examine transmission dynamics in a range of theoretical and real-world settings.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Hepatitis C Virus Dynamic Transmission Models Among People Who Inject Drugs

Woyesa¹,

Amente²

2023

IDR

View full text Add to dashboard Cite

Background: Transmission dynamic model is a concrete structure to describe and investigate the complex system of host-pathogen interactions. Hepatitis C virus (HCV) is a blood-borne virus that is transmitted from infectious to susceptible individuals when they come into contact with HCV-contaminated equipment. Injecting drug use is the most known transmission route, and about 80% of new HCV cases have been confirmed as having acquired HCV infection via drug injection. Objective: The main objective of this review paper was to review the importance of HCV dynamic transmission model, that enables the readers to understand the mechanism how HCV is transmissible from infectious to susceptible hosts and the effective controlling strategies. Methods: PubMed Central, Google Scholar, and Web of Science electronic databases have been used to search data by using key terms like "HCV transmission model among people who inject drug (PWID)", HCV potential herd immunity", and "basic reproductive number for HCV transmission in PWID." Data from research findings other than English version have been excluded from being used, and the most recently published data have been considered to be included. Conclusion:HCV belongs to the Hepacivirus genus within the Flaviviridae family. HCV infection is acquired when the susceptible individuals in populations come into contact with medical equipment such as shared syringes and needles, or swabs contaminated with infected blood. Construction of HCV transmission dynamic model is very significant in order to predict the duration and magnitude of its epidemic and to evaluate the potential impact of intervention. Comprehensive harm reduction and care/support service strategies are the best approach for intervention regarding HCV infection transmission among PWID.

show abstract

Section: Infectious Diseases Transmission Dynamic Modelsmentioning

confidence: 99%

Section: Infectious Diseases Transmission Dynamic Modelsmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Hepatitis C Virus Dynamic Transmission Models Among People Who Inject Drugs

Woyesa¹,

Amente²

2023

IDR

View full text Add to dashboard Cite

show abstract

“…Another pivot to the achievements and Stemming from the intersectorial stakeholder forum was the establishment of the Emergency Operation Center (EOC). [16] The EOC being "the control tower" of the response, functioned to synchronize the statewide response activities. The EOC served as the bridge between the field response and advocacy for political will with the Commissioner for Health being the Incident Manager for the outbreak chairs the EOC.…”

Section: Emergency Operation Centermentioning

confidence: 99%

“…The public enlightenment coordinated by the Ministry of Information and all media houses but led by a notable figure in this case state Governor signifying political will, engagement and participation. The state wide sensitization, awareness and health education campaigns across the 16 LGAs.…”

Section: Community Mobilization and Public Enlightenmentmentioning

confidence: 99%

Lassa Fever Outbreak in Southwestern Nigeria: The Ekiti State Response amidst Economic Recession

Adovi¹

2017

CAJPH

View full text Add to dashboard Cite

A confirmed case in a community requires prompt isolation of affected patients, good infection prevention and control practices, and rigorous contact tracing to stop outbreaks. This study depicts the highlights of the Ekiti state's response to its first confirmed Lassa fever outbreak. The approach used was a coordinated, and integrated rapid implementation of Lassa control measures using multidisciplinary teams. After with approproprate political will, Emmergency funds were rapidly mobilized. Seven response teams were constituted to mount an effective and high quality response. The Lassa fever Emergency Operations Centre (EOC) and incident management system was activated to effectively coordinate the response. Clinical, epidemiological, laboratory data, surveillance records and hospital statistics were analyzed during the outbreak. Daily situation reports of the response activities were disseminated to all stakeholders. Throughout the outbreak, the state recorded one confirmed case and nine suspected cases. Their age ranges from 17 years to 53 years with the median age of 25 years. Seventy (70%) of the cases were males. The state recorded 2 deaths during the outbreak but all had negative Laboratory results. The 10 cases were detected from four LGAs across the state. Seventy percent of the cases presented with acute fever (>38°C) while 60% presented with bleeding tendencies. Other major symptoms and signs that were common among the cases were sore throat and severe headache, and generalized weakness and muscle pain. The lessons learned support the significance of intersectorial collaboration and political will in response to outbreak at the provincial or state. However, challenges to control efforts included inadequate local laboratory capacity and fear among health workers, panic response among the general populace as well as deficient emergency preparedness.

show abstract