Investigating Demodex folliculorum in Patients with Urological Cancer

Kaya, Özlem Aycan; İnci, Melek; Yula, Erkan; Gökçe, Haşan; Rifaioğlu, Mehmet Murat; Demirtas, Onur; Yengil, Erhan

doi:10.5152/tpd.2012.50

Cited by 16 publications

(14 citation statements)

References 4 publications

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“…are also thought to play a role in chronic blepharitis-caused eye diseases (29). Their presence in patients with chronic renal disease, cancer, and immune deficiencies, such as those caused by malnutrition, suggests that they are an opportunistic parasite (30)(31)(32). However, when compared with control groups in previous studies, it has been shown that Demodex spp.…”

Section: Discussionmentioning

confidence: 99%

Demodex Species Infestation in Patients with Ear Itching and Its Relationship to Itch Severity

Bilal

Kirişçi²,

Özkaya³

2017

TurkiyeParazitolDerg

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Section: Discussionmentioning

confidence: 99%

Demodex Species Infestation in Patients with Ear Itching and Its Relationship to Itch Severity

Bilal

Kirişçi²,

Özkaya³

2017

TurkiyeParazitolDerg

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“…Parasite concentrations may increase due to suppressed immune system in these disease manifestations [10][11][12][13]. There are studies investigating the incidence of Demodex spp.…”

Section: Resultsmentioning

confidence: 99%

Demodex Parazytes in Schizophrenia

2016

Ann Clin Anal Med

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Anahtar KelimelerŞizofreni; İmmun Sistem; Ektoparazitik İnfestasyonlar Abstract Aim: Demodex parazytes are commonly present all over the world, especially in facial region of humans. Demodex spp. are assumed to be more common in schizophrenia due to partial suppression of immune system and lack of good self-care. The present study aimed to investigate the prevalence of Demodex ectoparasites in schizophrenia patients. Material and Method: In the study, 31 patients with a diagnosis of schizophrenia and 30 subjects without any psychiatric disorder or skin disease were subjected to standard superficial skin biopsy technique to determine Demodex spp. Results: Demodex spp.were found positive in nine schizophrenia patients and it was found positive in two healthy controls. Considering the prevalence of Demodex spp., a significant relationship is found between schizophrenia patients and normal controls (p<0.05). Discussion: As a result, Demodex spp. are more common in schizophrenia due conditions of reduced self-care and immunosuppression, Demodex parasites should be considered in schizophrenia patients with skin lesions, especially on the face, and should to be treated if needed.

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“…Both conditions were found to be associated with increased Demodex [24]. In the study analyzing the frequency of Demodex folliculorum infestation in patients with urological cancers, possible relationship between the cancer as the immunosuppressive state, and the increased Demodex folliculorum incidence was detected [25]. Demodex mites were also reported to be isolated from eyelashes and associated with blepharitis [26][27][28].…”

Section: Discussionmentioning

confidence: 98%

Pre-Treatment and Post-Treatment Demodex Densities in Patients under Immunosuppressive Treatments

et al. 2020

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Background and Objectives: Demodex species are common obligatory parasites and normally present in low number in human beings. Immunosuppression was suggested to be associated with increased density of Demodex mites. Systemic glucocorticoids, cyclosporine, methotrexate, and azathioprine are commonly used immunosuppressive agents. We aim to determine the pre- and post-treatment Demodex densities in patients receiving immunosuppressive therapy and compare with those of healthy subjects. Materials and Methods: Demodex density was investigated at the beginning, first, and third months of the immunosuppressive therapy in 45 patients who received methotrexate, cyclosporine, systemic steroid, or azathioprine treatments and in 45 healthy subjects at the same time as the patients. Five standardized skin surface biopsies were taken from cheeks, forehead, nose, and chin of the patients and control group. The presence of five or more parasites in 1 cm2 area was considered as positive. Results: Demodex test was negative at the beginning of the treatment in all patients. Demodex test was positive in one patient in the first and third months of treatment and in three patients only in the third month of treatment. In the control group, Demodex test was determined as positive in just one healthy individual at the beginning, first and third months of the study. When the patient and control groups were evaluated in terms of Demodex number, there was a statistically significant difference in Demodex density in patients treated with immunosuppressive treatment in the first and third months when compared with the control group (p < 0.05). Conclusion: Immunosuppressive treatment might increase the number of Demodex mites and demodicidosis should be kept in mind in patients on immunosuppressive treatment.

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Investigating Demodex folliculorum in Patients with Urological Cancer

Abstract: It should be kept in mind that D. folliculorum incidence may increase in immunosuppressive states, such as cancer.

Cited by 16 publications

References 4 publications

Demodex Species Infestation in Patients with Ear Itching and Its Relationship to Itch Severity

Demodex Species Infestation in Patients with Ear Itching and Its Relationship to Itch Severity

Demodex Parazytes in Schizophrenia

Pre-Treatment and Post-Treatment Demodex Densities in Patients under Immunosuppressive Treatments

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