Investigating accuracy of 3D printed liver models with computed tomography

Witowski, Jan; Wake, Nicole; Grochowska, Anna; Sun, Zhonghua; Budzyński, Andrzej; Major, Piotr; Popiela, T; Pędziwiatr, Michał

doi:10.21037/qims.2018.09.16

Cited by 43 publications

(41 citation statements)

References 29 publications

(32 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We followed a cost-effective method of developing full-sized 3DP liver models introduced by Witowski et al [13]. Accuracy of this approach has been previously confirmed [14]. Fifteen out of 19 patients have been previously reported in the latter study.…”

Section: Methodsmentioning

confidence: 93%

Decision-making based on 3D printed models in laparoscopic liver resections with intraoperative ultrasound: a prospective observational study

et al. 2019

Self Cite

View full text Add to dashboard Cite

Objectives The aim of this study was to evaluate impact of 3D printed models on decision-making in context of laparoscopic liver resections (LLR) performed with intraoperative ultrasound (IOUS) guidance. Methods Nineteen patients with liver malignances (74% were colorectal cancer metastases) were prospectively qualified for LLR or radiofrequency ablation in a single center from April 2017 to December 2018. Models were 3DP in all cases based on CT and facilitated optical visualization of tumors' relationships with portal and hepatic veins. Planned surgical extent and its changes were tracked after CT analysis and 3D model inspection, as well as intraoperatively using IOUS. Results Nineteen patients were included in the analysis. Information from either 3DP or IOUS led to changes in the planned surgical approach in 13/19 (68%) patients. In 5/19 (26%) patients, the 3DP model altered the plan of the surgery preoperatively. In 4/19 (21%) patients, 3DP independently changed the approach. In one patient, IOUS modified the plan post-3DP. In 8/19 (42%) patients, 3DP model did not change the approach, whereas IOUS did. In total, IOUS altered surgical plans in 9 (47%) cases. Most of those changes (6/9; 67%) were caused by detection of additional lesions not visible on CT and 3DP. Conclusions 3DP can be helpful in planning complex and major LLRs and led to changes in surgical approach in 26.3% (5/19 patients) in our series. 3DP may serve as a useful adjunct to IOUS. Key Points • 3D printing can help in decision-making before major and complex resections in patients with liver cancer. • In 5/19 patients, 3D printed model altered surgical plan preoperatively. • Most surgical plan changes based on intraoperative ultrasonography were caused by detection of additional lesions not visible on CT and 3D model.

show abstract

Section: Methodsmentioning

confidence: 93%

Decision-making based on 3D printed models in laparoscopic liver resections with intraoperative ultrasound: a prospective observational study

et al. 2019

Self Cite

View full text Add to dashboard Cite

show abstract

“…A number of studies have demonstrated encouraging results of the usefulness of 3D printed liver models which serve as valuable tools for pre-surgical planning, intraoperative orientation and simulation purposes (16)(17)(18)(19)(20). However, a recent systemic review highlights the limited studies involving quantitative assessment of the accuracy of 3D printed liver models (21).…”

Section: A B C Dmentioning

confidence: 99%

“…3D printed liver models have been confirmed to overcome limitations of traditional computed tomography (CT) or magnetic resonance imaging (MRI) imaging by providing accurate assessment of complex hepatic anatomy and pathology, and assisting selection of appropriate surgical procedures for hepatic tumors or liver transplantation (16)(17)(18)(19)(20). A recent systematic review has analyzed 19 studies of reporting the usefulness of 3D printed liver models in the simulation of liver surgeries (21).…”

Section: Introductionmentioning

confidence: 99%

Patient-specific 3D printed model of biliary ducts with congenital cyst

Allan¹,

Kealley²,

Squelch³

et al. 2019

Quant. Imaging Med. Surg

Self Cite

View full text Add to dashboard Cite

Background: 3D printing has shown great promise in medical applications, with increasing reports in liver diseases. However, research on 3D printing in biliary disease is limited with lack of studies on validation of model accuracy. In this study, we presented our experience of creating a realistic 3D printed model of biliary ducts with congenital cyst. Measurements of anatomical landmarks were compared at different stages of model generation to determine dimensional accuracy. Methods: Contrast-enhanced computed tomography (CT) images of a patient diagnosed with congenital cyst in the common bile duct with dilated hepatic ducts were used to create the 3D printed model. The 3D printed model was scanned on a 64-slice CT scanner using the similar abdominal CT protocol. Measurements of anatomical structures including common hepatic duct (CHD), right hepatic duct (RHD), left hepatic duct (LHD) and the cyst at left to right and anterior to posterior dimensions were performed and compared between original CT images, the standard tessellation language (STL) image and CT images of the 3D model. Results: The 3D printing model was successfully generated with replication of biliary ducts and cyst. Significant differences in measurements of these landmarks were found between the STL and the original CT images, and the CT images of the 3D printed model and the original CT images (P<0.05). Measurements of the RHD and LHD diameters from the original CT images were significantly larger than those from the CT images of 3D model or STL file (P<0.05), while measurements of the CHD diameters were significantly smaller than those of the other two datasets (P<0.05). No significant differences were reached in measurements of the CHD, RHD, LHD and the biliary cyst between CT images of the 3D printed model and STL file (P=0.08-0.98). Conclusions: This study shows our experience in producing a realistic 3D printed model of biliary ducts and biliary cyst. The model was found to replicate anatomical structures and cyst with high accuracy between the STL file and the CT images of the 3D model. Large discrepancy in dimensional measurements was noted between the original CT and STL file images, and the original CT and CT images of the 3D model, highlighting the necessity of further research with inclusion of more cases of biliary disease to validate accuracy of 3D printed biliary models.

show abstract

“…Of the other 4 original studies, 2 reported the quantitative assessment of model accuracy of liver and biliary anatomical structures and pathologies (23,24). 3D printed models are proved to assist pre-surgical planning and simulation of hepatobiliary disease (25,26), and these two studies offered further evidence of model accuracy in delineating anatomies.…”

mentioning

confidence: 99%

“…3D printed models are proved to assist pre-surgical planning and simulation of hepatobiliary disease (25,26), and these two studies offered further evidence of model accuracy in delineating anatomies. Witowski et al created 15 patientspecific 3D printed liver models including normal hepatic structures and tumours (23). These 3D printed models were CT scanned with analyses compared to those from original CT images in terms of liver parenchyma and tumour volume, as well as diameter and length measurements of hepatic structures.…”

mentioning

confidence: 99%