Inverted Takotsubo Cardiomyopathy Associated With the Consumption of a Weight Management Supplement

Abstract

Inverted takotsubo cardiomyopathy (ITC) is a rare disease that has a strong association with pheochromocytoma and intracranial hemorrhage. We describe the case of a patient who developed ITC after an extra dose, along with chronic exposure, of a weight management supplement containing caffeine and amphetamine-like stimulants, a combination that could potentially raise the local sympathetic tone of the myocardium. The patient was managed conservatively and recovered in 2 months. This report emphasizes the importance of the awareness of the potential association between ITC and the consumption of caffeine and amphetamine-like stimulants. CJC Open 2 (2020) 26e29Ethics Statement: The case reported has adhered to the Helsinki ethical principles for medical research involving human beings.

Simultaneous occurrence of transient global amnesia and Takotsubo syndrome triggered by caring for a terminally ill relative

“…TTS has been reported after ingestion of a weight management supplement containing caffeine and amphetamine-like stimulants. 26 In a further case, TTS occurred after a combined drug intoxication containing acetaminophen. 27 We conclude that TTS and TGA can occur simultaneously, not only in the context of acute but also chronic emotional stress.…”

“…The comedication of our patient may possibly have contributed to the development of TTS. TTS has been reported after ingestion of a weight management supplement containing caffeine and amphetamine‐like stimulants 26 . In a further case, TTS occurred after a combined drug intoxication containing acetaminophen 27 …”

Simultaneous occurrence of transient global amnesia and takotsubo syndrome triggered by caring for a terminally ill relative

“…TTS has been reported after ingestion of a weight management supplement containing caffeine and amphetamine-like stimulants. [20] In a further case, TTS occurred after a combined drug intoxication containing acetaminophen. [21] We conclude that TTS and TGA can occur simultaneously even after long-standing stressors.…”

Reversible Takotsubo Syndrome Complicated With Acute Thromboembolic Stroke Co-Occurring With Cola-Induced Severe Hypokalemia

“…For instance, TTS has been associated with severe hypokalemia secondary to primary aldosteronism and decreased oral intake [ 10 , 11 ]. Furthermore, excessive caffeine consumption from energy drinks and weight loss supplements has been linked to the occurrence of TTS [ 12 , 13 ]. However, to the best of our knowledge, there have been no reports of coexistent TTS with cola-induced severe hypokalemia.…”