Inverted papilloma of the nose and paranasal sinuses: a study of 67 patients

Abstract

Retrospectively, 67 patients with inverted nasal papillomas were studied. In 12, the lesions were localized exclusively on the nasal septum. In 55, the lesion involved the lateral wall and/or the paranasal sinuses. There was a male predominance of 3:1. After histological revision the most dominating epithelial type was found to be transitional. Inverted papilloma was in one patient associated with squamous cell carcinoma. Ten per cent suffered recurrences from 6 to 37 months after the primary surgical procedure. We found that limited septal lesions could be managed by an intranasal procedure but lateral rhinotomy is recommended as the procedure of choice in the treatment of inverted papilloma of the lateral wall.

Skull Base Inverted Papilloma: A Comprehensive Review

“…IP most commonly arises from the lateral nasal wall [63–66]. Incidence of isolated sphenoid IP is exceedingly low [46–55, 67, 68].…”

“…The lining consists of multilayered nonkeratinized squamous epithelium with scattered mucous cells and microcysts filled with neutrophils. The covering epithelium can be squamous, respiratory, or transitional cell epithelium or a combination of all three [66]. The cells show minimal nuclear atypia with the typical basilar layer mitosis.…”

“…The peak incidence is in the fifth and sixth decades of life [211, 227, 228], but it has been reported in all age groups [6, 229, 230]. Clearly, men are affected more often than women [3, 228, 231, 232] with a 3 to 1 male to female predominance ratio [66, 230]. Caucasians are more commonly affected—white persons are most at risk, compared with persons of other races.…”

Schneiderian Papillomas and Nonsalivary Glandular Neoplasms of the Head and Neck

“…Inverted papillomas (IP) are two to five times more common in males and are found primarily in the 40 -70-year age group (2,3,8,14,15,(23)(24)(25)(26)(27)(28)(29)(30). The 6-year-old boy included in the series of Eavey (31) is one of the youngest patients yet described with this papilloma.…”

Bilateral inverted papilloma: A report of two cases and review of the current literature

“…Traditional teaching has been to treat inverted papilloma with aggressive surgery in the form of a lateral rhinotomy and medial maxillectomy in an effort to limit recurrence [11,12,17,18]. However, over the last decade many reports have emerged using endoscopic techniques [9,[19][20][21][22] with rates of recurrence averaging out at 13.4%.…”