Inverse Relationship between Lipid-lowering Drugs and Saturated Fat Intake in US Adults

Mann, David; Natarajan, Sundar

doi:10.1007/s10557-007-6013-7

Cited by 4 publications

(13 citation statements)

References 22 publications

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“…Statinusers also perceived cardiovascular disease to be more severe than non-statin users. This is in accordance with existing research which suggests that the initiation of statin-use may increase risk perception (16,20).…”

Section: Thinking About Risksupporting

confidence: 93%

“…We found that statin-use was not on its own associated with the adoption of a low-fat diet. This is in accordance with the findings of three American studies (16,17,43). However, despite finding no significant differences in the dietary fat intake of statin users and non-statin users, one of the aforementioned American studies did find that statin users consumed significantly fewer fruits, vegetables and vitamins.…”

Section: Statin Use and Dietsupporting

confidence: 89%

“…The increased physical inactivity found among the statin users in this study contrasts with the findings of two American studies and one Swedish study. The American studies both found no difference in the physical activity levels of statin users and non-statin users (16,43). The Swedish study found significantly healthier exercise behaviours among statin users than among non-statin users (20).…”

Section: Statin Use and Exercisementioning

confidence: 96%

“…There is sparse and conflicting data available on the relationship between statin-use and the adoption of healthy lifestyle choices (16). Some researchers claim that statin-use provides a false sense of security, enabling people to neglect lifestyle modifications and continue to make poor lifestyle choices (17)(18)(19).…”

Section: Introductionmentioning

confidence: 99%

“…Some researchers claim that statin-use provides a false sense of security, enabling people to neglect lifestyle modifications and continue to make poor lifestyle choices (17)(18)(19). Others have either found no difference or found that statin users consumed less dietary fat than non-statin users (16,20). As statin-use increases, it is important to assess whether there is an interaction between statin-use and the adoption of healthy lifestyle choices for a variety of reasons.…”

Section: Introductionmentioning

confidence: 99%

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The association between statin-use and diet, exercise, and perceptions of high cholesterol in urban and semi-urban Nigerians: a cross-sectional study.

Coker

hill

Otu

et al. 2019

Preprint

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Background The rise of cardiovascular diseases in sub-Saharan Africa strains fragile healthcare systems. Cardiovascular disease prevention involves the use of prophylactic medications like statins and the adoption of healthy lifestyle choices. However, the nature of the relationship between statin-use and the adoption of healthy lifestyle choices remains unclear. This study is the first to examine whether there is a relation between statin-use, the adoption of a low-fat diet and healthy exercise behaviours, and the way Nigerians diagnosed with hyperlipidaemia think about high cholesterol as a risk factor for cardiovascular disease. Methods This cross-sectional study was conducted in an urban site and a semi-urban site in Nigeria. Questionnaires were used to compare the dietary and exercise behaviours; perceptions of high cholesterol; and perceived future risk of cardiovascular disease of 78 statin users and 70 non-statin users. Results The majority (69%) of participants reported that they had adopted a low-fat diet. However, 80% participants were classified as inactive/moderately inactive and statin users were significantly less active than non-statin users (86% of statin users inactive/moderately inactive vs 74% of non-statin users, X2 =3.852, p=0.05). A logistic regression model found that odds of adopting a low-fat diet was 5 times greater in participants recruited from the urban research site (95% CI=1.7 to 12.5, p=0.003) and increased as reported perceived statin control of high cholesterol increased (OR=2.33, 95% CI=1.16 to 4.69, p=0.018). Conclusions The odds of adopting a low-fat diet increased as statin control perceptions increased - suggesting that statin-use and the adoption of healthy dietary choice were thought to work in unison to manage high cholesterol. Urban-dwellers were more likely to have adopted healthy dietary choices and to think about adopting exercise choices than semi-urban dwellers. This demonstrates a growing awareness of negative future impacts of Westernised lifestyle behaviours in urban areas and the need for public health interventions in semi-urban areas to raise awareness and facilitate the adoption of healthy lifestyle choices in order to curtail the rise of cardiovascular disease in Nigeria.

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Section: Thinking About Risksupporting

confidence: 93%

Section: Statin Use and Dietsupporting

confidence: 89%