Inverse Finite Element Modeling for Characterization of Local Elastic Properties in Image-Guided Failure Assessment of Human Trabecular Bone

Zwahlen, Alexander; Christen, D. K.; Ruffoni, Davide; Schneider, Philipp; Schmölz, Werner; Müller, Ralph

doi:10.1115/1.4028991

Cited by 14 publications

(13 citation statements)

References 75 publications

(76 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Without the ability to assess tissues at risk of failure properly, however, corrective action may be misguided or incomplete. As a result, failure analysis and modeling have become increasingly active research areas [1][2][3][4].…”

Section: Introductionmentioning

confidence: 99%

Isotropic Failure Criteria Are Not Appropriate for Anisotropic Fibrous Biological Tissues

Korenczuk

Votava

Dhume

et al. 2017

Journal of Biomechanical Engineering

View full text Add to dashboard Cite

The von Mises (VM) stress is a common stress measure for finite element models of tissue mechanics. The VM failure criterion, however, is inherently isotropic, and therefore may yield incorrect results for anisotropic tissues, and the relevance of the VM stress to anisotropic materials is not clear. We explored the application of a well-studied anisotropic failure criterion, the Tsai–Hill (TH) theory, to the mechanically anisotropic porcine aorta. Uniaxial dogbones were cut at different angles and stretched to failure. The tissue was anisotropic, with the circumferential failure stress nearly twice the axial (2.67 ± 0.67 MPa compared to 1.46 ± 0.59 MPa). The VM failure criterion did not capture the anisotropic tissue response, but the TH criterion fit the data well (R2 = 0.986). Shear lap samples were also tested to study the efficacy of each criterion in predicting tissue failure. Two-dimensional failure propagation simulations showed that the VM failure criterion did not capture the failure type, location, or propagation direction nearly as well as the TH criterion. Over the range of loading conditions and tissue geometries studied, we found that problematic results that arise when applying the VM failure criterion to an anisotropic tissue. In contrast, the TH failure criterion, though simplistic and clearly unable to capture all aspects of tissue failure, performed much better. Ultimately, isotropic failure criteria are not appropriate for anisotropic tissues, and the use of the VM stress as a metric of mechanical state should be reconsidered when dealing with anisotropic tissues.

show abstract

Section: Introductionmentioning

confidence: 99%

Isotropic Failure Criteria Are Not Appropriate for Anisotropic Fibrous Biological Tissues

Korenczuk

Votava

Dhume

et al. 2017

Journal of Biomechanical Engineering

View full text Add to dashboard Cite

show abstract

“…El tamaño del tubo debía ser menor a 50 mm. El límite lo imponía el tamaño de las vértebras y el espacio restante mínimo necesario cercano al taladro para que las piezas no quedasen dañadas (14) (15). Se optó por elegir un diámetro de 44 mm con un espesor de 2,7 mm, puesto que era el canto más grande que se encontraba en stock.…”

Section: Buscando La Formaunclassified

«La ballena vuelve al museo»; proceso de diseño y cálculo de una estructura ligera

Calvo

2017

Inf. constr.

View full text Add to dashboard Cite

Cómo citar este artículo/Citation: Costales Calvo, I. (2016). «La ballena vuelve al museo»; proceso de diseño y cálculo de una estructura ligera. Informes de la Construcción, 69(546) RESUMENEl texto describe el proceso de diseño y cálculo de una estructura metálica ligera que soporta otra estructura aún más ligera: el esqueleto de una ballena. Una pieza que ha sido conservada durante más de 150 años. Se encuentra suspendida de otra estructura metálica bidireccional y singular, que resuelve grandes luces: el techo del edificio Fòrum 2004 de Barcelona. Para encontrar la solución más adecuada se ha utilizado un programa de cálculo no lineal. Gracias a un diseño eficiente y a un exhaustivo análisis se ha conseguido que la estructura principal trabaje a tracción, eliminando la posibilidad de pandeo, reduciendo así la sección resultante a la necesaria para trabajar a flexo-tracción, por lo que la estructura ha podido quedar oculta dentro del esqueleto. Durante la fase de diseño se hicieron propuestas adecuadas para poder transportar las piezas y soldarlas o ensamblarlas fácilmente. Finalmente se describe la puesta en obra de la estructura, que se realizó en un fin de semana, para poder sostener a uno de los iconos más queridos por los niños de Barcelona: «La balena Brava».Palabras clave: esqueleto; ballena; diseño estructural; estructura tensada; sistema no lineal; estructura ligera; puesta en obra. ABSTRACT

show abstract

“…For bone, image registration has been used for various purposes, including improving the reproducibility of high-resolution computed tomography (CT) derived bone parameters [5], strain mapping of loaded bone [6], and for the analysis of sites of bone formation and resorption at the tibia [7] and finger joints. [8] For fractured bone, Lynch et al applied image registration to longitudinal CT images of healing distal radius fractures to assess changes in CT image intensity within the fracture gap during the healing process[9], and Tassani et al used image registration to automatically detect the fracture zone in microCT images of trabecular bone.…”

Section: Introductionmentioning

confidence: 99%

“…[5, 7–10] Zwahlen et al, however, used a deformable (non-rigid) image registration approach because of local deformation of individual trabeculae. [6]…”

Section: Introductionmentioning

confidence: 99%

Feasibility of rigid 3D image registration of high-resolution peripheral quantitative computed tomography images of healing distal radius fractures

et al. 2017

Self Cite

View full text Add to dashboard Cite

For accurate analysis of bone formation and resorption during fracture healing, correct registration of follow-up onto baseline image is required. A per-fragment approach could improve alignment compared to standard registration based on the whole fractured region. In this exploratory study, we tested the effect of fragment size and displacement on a per-fragment registration, and compared the results of this per-fragment registration to the results of the standard registration in two stable fractures and one unstable fracture.To test the effect of fragment size and displacement, high-resolution peripheral quantitative computed tomography (HR-pQCT) scans of three unfractured radii were divided into subvolumes. Different displacements in x-, y, or z-direction or rotations around each axis were applied, and each subvolume was registered onto the initial volume to realign it. Next, registration of follow-up onto baseline scan was performed in two stable and one unstable fracture. After coarsely aligning the follow-up onto the baseline scan, a more accurate registration was performed of the whole fracture, i.e. the standard registration, and of each fracture fragment separately, i.e. per-fragment registration. Alignment was checked using overlay images showing baseline, follow-up and overlap between these scans, and by comparing correlation coefficients between the standard and per-fragment registration.Generally, subvolumes as small as 300 mm3 that were displaced up to 0.82 mm in x- or y-, or up to 1.64 mm in z-direction could be realigned correctly. For the fragments of all fractures, correlation coefficients were higher after per-fragment registration compared to standard registration. Most improvement was found in the unstable fracture and one fragment of the unstable fracture did not align correctly.This exploratory study showed that image registration of individual subvolumes, such as fracture fragments, is feasible in both stable and unstable fractures, and leads to better alignment of these fragments compared to an approach that is based on registration using the whole fractured region. This result is promising for additional analysis of bone formation and resorption in HR-pQCT studies on fracture healing.

show abstract

Inverse Finite Element Modeling for Characterization of Local Elastic Properties in Image-Guided Failure Assessment of Human Trabecular Bone

Cited by 14 publications

References 75 publications

Isotropic Failure Criteria Are Not Appropriate for Anisotropic Fibrous Biological Tissues

Isotropic Failure Criteria Are Not Appropriate for Anisotropic Fibrous Biological Tissues

«La ballena vuelve al museo»; proceso de diseño y cálculo de una estructura ligera

Feasibility of rigid 3D image registration of high-resolution peripheral quantitative computed tomography images of healing distal radius fractures

Contact Info

Product

Resources

About