Inverse association of MRI-derived native myocardial T1 and perfusion reserve index in women with evidence of ischemia and no obstructive CAD: A pilot study

Abstract

Symptomatic women with INOCA have elevated native T1 compared to matched reference controls and there is a significant association between elevated native T1 and impaired MPRI, considered a surrogate measure of ischemia severity in this cohort. Future studies in a larger cohort are needed to elucidate the mechanism underlying this inverse relationship.

Cardiovascular disease in women: insights from magnetic resonance imaging

“…CMR studies in women with signs and symptoms of ischemia with or without obstructive CAD have made a number of observations, including the presence of increased native T1 values compared to controls, which was associated with reduced myocardial perfusion reserve index (MPRI), a potential surrogate measure of ischemia severity [64].…”