Invasive Upper Urinary Tract Urothelial Carcinoma With Atypical Clinic: Case Report

Abstract

Key words: invasive upper tract urothelial carcinoma, radical nephroureterectomy, chemotherapy treatment. Based on literature sources Urothelial carcinomas (UCs) are the fourth most common tumors. They can be located in the lower (bladder and urethra) or upper (pyelocaliceal cavities and ureter) urinary tract. Herein, we report a rare case of upper tract high malignancy urothelial carcinoma with atypical clinic which looks like an apostematous pyelonephritis. Upper tract urothelial carcinomas that invade the muscle wall usually have poor prognosis. Retrospectively assessing our patient has the most common symptoms of urinary tract infection and malignancy. It was non-visible hematuria, flank pain, chronic urinary tract infection, and also systemic symptoms (including anorexia, weight loss, malaise, fatigue, fever, and night sweats). The right diagnose we have determined by biopsy and CTU. Open RNU with bladder cuff excision is the standard for high-risk UTUC, regardless of tumor location and bladder cuff removal is imperative. AC adjuvant chemotherapy is the most widely used treatment in patients with cancer after undergoing surgery. Unfortunately the overall survival rate of urothelial metastatic tumor for this day is poor.