Invasive Thyroid Cancer: Management of the Trachea and Esophagus

Price, Daniel L.; Wong, Richard J.; Randolph, Gregory W.

doi:10.1016/j.otc.2008.08.002

Cited by 76 publications

(66 citation statements)

References 60 publications

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“…However, the indications are rigid: the glottis must be functional and patients should not have severe pulmonary pathology (6). To avoid circumferential mobilization of the trachea or larynx, a total of 5 to 6 cm of trahea may be resected and primary reanastomosis performed (7). In the present study, as the tumor had invaded a 5-cm stretch of the trachea and extended to the substernal area, tracheal resection and reconstruction was not only difficult but also dangerous.…”

Section: Discussionmentioning

confidence: 70%

Emergency management of a patient with severe airway obstruction resulting from poorly differentiated thyroid carcinoma: A case report

Yang

et al. 2012

Oncology Letters

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Abstract. We present a case of a life-threatening almost complete airway obstruction resulting from poorly differentiated thyroid carcinoma in a 48-year-old male. Airway obstruction may lead to unexpected mortality by suffocation and patients with poorly differentiated thyroid carcinoma usually have a fast deterioration and fatal outcome. In the case presented, we describe a safe and effective treatment strategy. Assisted by femoro-femoral cardiopulmonary bypass oxygenation, a tracheal stent was implanted successfully. Following surgery there were no complications, and chemoradiotherapy resulted in the relief of obstructing symptoms and improved the quality of life of the patient. This case indicates that femoro-femoral cardiopulmonary bypass provides adequate oxygen support to undergo further management and that tracheal stent implant is an effective emergent measure to relieve severe airway obstruction in patients with poorly differentiated thyroid carcinoma.

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Section: Discussionmentioning

confidence: 70%

Emergency management of a patient with severe airway obstruction resulting from poorly differentiated thyroid carcinoma: A case report

Yang

et al. 2012

Oncology Letters

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“…In the 1980s and early 1990s, diagnosis and evaluation of papillary carcinoma was completely reformed. Ultrasound is standard at most institutions for the initial evaluation of thyroid disease and can be combined with fine-needle aspiration biopsy for diagnostic purposes [8,[29][30][31]. When extrathyroidal extension of thyroid cancer is suspected, based on the patient's history or physical examination, cross-sectional imaging with CT or MRI is essential.…”

Section: Discussionmentioning

confidence: 99%

“…In contrast the high grade malignancies show rapid growth and spread, with death being almost inevitable within 2 years [5,6]. Adverse prognostic factors have been well-established and include age, extra-thyroidal extension, tumor histology, primary tumor size, and distant metastasis [7,8]. Extra-thyroidal extension has the greatest negative impact on prognosis.…”

Section: Introductionmentioning

confidence: 99%

Well-Differentiated Thyroid Carcinoma Invading the Larynx and Trachea

Laus¹

2013

CMR

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Larynx and trachea invasion by thyroid cancer is an uncommon but difficult problem. There is no consensus on indication for the extent of surgery, particularly when there is a requirement for airway reconstruction. In general, the surgeon must decide between a complete ablation of the tumor at the cost of large-mutilation and a less radical dissection that leaves residual tumor to be treated with radiation therapy and additional radio-iodine.

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“…Details of specific surgical procedures are beyond the scope of this article and are well reported elsewhere (28,29). However, in order to manage such cases appropriately, the treating team should have experience with advanced techniques of resection and reconstruction (30).…”

Section: Surgical Managementmentioning

confidence: 99%

“…When the larynx is invaded, disease is often well lateralized and can be excised with a partial laryngectomy. However, extensive laryngeal invasion, particularly when comorbid respiratory disease is present, will require total laryngectomy (28).…”

Section: Invasion Of the Airwaymentioning

confidence: 99%