Invasive Thymoma Causing Acute St-Segment Elevation Myocardial Infarction

Raju, P. Krishnam; Nair, Ranjit; Kaid, Khalil

doi:10.1378/chest.134.4_meetingabstracts.c1003

Cited by 3 publications

(2 citation statements)

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“…Those who present with symptoms are widely variable, and most patients present with compressive symptoms due to local mass effect (e.g., cough, shortness of breath, chest discomfort, phrenic nerve palsy), constitutional symptoms (weight loss, fever, night sweats), or paraneoplastic syndromes, with myasthenia gravis being the most commonly associated [ 7 , 8 ]. Thymomas personating as acute coronary events are uncommon, and most reports in the literature are due to tumor invasion of adjacent cardiac structures [ [9] , [10] , [11] ]. Only a few reports have described a thymoma resulting in myocardial infarction without physical infiltration to the heart or pericardium [ 12 ], as in our case.…”

Section: Discussionmentioning

confidence: 99%

Non-ST-segment elevation myocardial infarction with non-obstructive coronary arteries due to a type-A thymoma: A case report

Tsai

Chang

Yeh

et al. 2023

Heliyon

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Section: Discussionmentioning

confidence: 99%

Non-ST-segment elevation myocardial infarction with non-obstructive coronary arteries due to a type-A thymoma: A case report

Tsai

Chang

Yeh

et al. 2023

Heliyon

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“…Bylo popsáno srdeční selhání na podkladě invaze tumoru do myokardu, 7 myokarditida s perikardiálním výpotkem a srdeční tamponádou, 8 myokarditida s kompletní atrioventrikulární (AV) blokádou, 9 okluze koronární tepny tumorózní masou. 10 Také byl popsán případ thymomu asociovaného s myasthenia gravis, kdy thymom nebyl v přímém kontaktu se srdcem, na EKG byly změny úseku ST, které po léčbě ustoupily a EKG se normalizovalo. 11 V diagnostice thymomů se uplatňují prostý snímek hrudníku, výpočetní tomografi e (CT) či magnetická rezonance.…”

Section: Diskuseunclassified

(ST segment elevations caused by invasion of carcinoma of the thymus to the myocardium)

et al. 2019

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Patologické elevace úseku ST na 12svodovém EKG jsou ve většině případů způsobeny ischemickou chorobou srdeční. Elevace úseku ST na EKG mohou být i neischemické etiologie při jiném kardiálním onemocnění. Existují i vzácné příčiny elevace ST nekardiálního původu. V této kazuistice autoři prezentují případ 68letého pacienta s karcinomem thymu, který prorůstal do srdečních struktur a byl příčinou patologických elevací ST na EKG.

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A rare cause of myocardial infarction with non-obstructive coronary arteries—case report of ST-segment elevation myocardial infarction caused by a mediastinal mass

Gue

Anwar

Gorog

2018

European Heart Journal - Case Reports

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IntroductionST-segment elevation myocardial infarction (STEMI) is attributable to an occluded coronary artery in almost 90% of patients. Accordingly, restoration of coronary perfusion as early as possible, preferably with primary percutaneous coronary intervention, is the recommended treatment by the European Society of Cardiology, to maximise myocardial salvage. However, not all cases of STEMI are because of coronary artery occlusion. ST-segment elevation myocardial infarction that occurs in the absence of obstructive coronary artery disease on angiography has been termed myocardial infarction with non-obstructive coronary arteries (MINOCA).Case presentationA 44-year-old man was admitted with retrosternal chest pain radiating to the left arm and jaw, and electrocardiography showed extensive anterior ST-segment elevation. Emergency coronary angiography showed all three coronary arteries were patent with Thrombolysis in Myocardial Infarction-3 flow and no evidence of dissection or thrombus. The ST-elevation and pain resolved spontaneously. Troponin-T level rose from <3 ng/L on arrival to 549 ng/L at 12 h. Subsequent cardiac magnetic resonance imaging (MRI) showed a structurally normal heart (without late gadolinium enhancement) but detected an incidental large, lobulated (90 × 31 × 71 mm) mediastinal mass containing multiple cysts in the anterior mediastinum with inflammation and oedema of the parietal pericardium. Tissue biopsy confirmed Hodgkin’s lymphoma and the patient was initiated on chemotherapy.DiscussionSome 3% of ST-segment myocardial infarctions occur in the absence of obstructive coronary disease (MINOCA), is more frequent in younger patients. Cardiac MRI is a useful tool to both identify some of the potential causes of MINOCA and also to confirm the diagnosis of infarction. Some 26% of MINOCA patients have significant biochemical evidence of myocardial injury but have a normal cardiac MRI. This case illustrates a very rare cause of myocardial infarction in a young patient with unobstructed coronary arteries, and highlights the need in such cases for further detailed imaging of the myocardium and thorax to establish the diagnosis and initiate appropriate treatment.

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Invasive Thymoma Causing Acute St-Segment Elevation Myocardial Infarction

Cited by 3 publications

References 0 publications

Non-ST-segment elevation myocardial infarction with non-obstructive coronary arteries due to a type-A thymoma: A case report

Non-ST-segment elevation myocardial infarction with non-obstructive coronary arteries due to a type-A thymoma: A case report

(ST segment elevations caused by invasion of carcinoma of the thymus to the myocardium)

A rare cause of myocardial infarction with non-obstructive coronary arteries—case report of ST-segment elevation myocardial infarction caused by a mediastinal mass

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