“…nutritional plasticity, reproductive success, and tolerance to environmental stressors), the ability to manipulate pH via the secretion of low molecular weight organic acids, and in particular, oxalic acid, has been largely ignored in the context of human pathogenesis. Several clinical reports have shown the presence of calcium oxalate crystals in pulmonary aspergillosis in animals and humans (Kurrein et al, 1975; Maeno et al, 2015; Muntz, 1999; Oda et al, 2013; Payne et al, 2017; Yi et al, 2019). Oxalic acid and oxalate crystals are thought to directly cause damage to the host tissues (including pulmonary blood vessels), and to generate free radicals which can harm cells indirectly (Payne et al, 2017).…”