2012
DOI: 10.1007/s12098-012-0855-0
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Invasive Meningococcal Infection: Analysis of 110 cases from a Tertiary Care Centre in North East India

Abstract: This is the first epidemic report of invasive meningococcal disease from the north east India. Chloramphenicol acts well in areas with penicillin or cephalosporin resistance. Mortality reduces significantly with early diagnosis and prompt intervention.

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Cited by 24 publications
(54 citation statements)
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References 22 publications
(19 reference statements)
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“…Other potential causes of optic neuritis in children include Leber's hereditary optic neuropathy and infectious causes (Bartonella, syphilis, lyme, Toxocara, and toxoplasmosis). Recent reports have additionally cited optic neuritis as a manifestation of biotinidase deficiency or invasive meningococcal infection [10,11]. Optic neuritis has also been reported in otherwise healthy children following vaccine, as recently reported with H1N1 vaccination in Japan [12].…”
Section: Epidemiologymentioning
confidence: 85%
“…Other potential causes of optic neuritis in children include Leber's hereditary optic neuropathy and infectious causes (Bartonella, syphilis, lyme, Toxocara, and toxoplasmosis). Recent reports have additionally cited optic neuritis as a manifestation of biotinidase deficiency or invasive meningococcal infection [10,11]. Optic neuritis has also been reported in otherwise healthy children following vaccine, as recently reported with H1N1 vaccination in Japan [12].…”
Section: Epidemiologymentioning
confidence: 85%
“…NM forma parte de la flora comensal nasofaríngea en el 5-15% de los adultos 6 . Sin embargo, es reconocida por cuadros infecciosos invasivos potencialmente graves, clásicamente meningitis, con o sin meningococcemia, en pacientes pediátricos principalmente menores de un año y adolescentes/adultos jóvenes, que ocasionalmente pueden complicarse con focos secundarios extra-meníngeos [1][2][3] . Por otro lado, en la literatura extranjera, se han descrito algunos casos de infecciones extra-meníngeas por NM, como laringitis, artritis, pericarditis y neumonía, sin meningitis asociada, en pacientes principalmente geriátricos o con alguna comorbilidad [4][5][6][7][8][9][10] .…”
Section: Discussionunclassified
“…as infecciones graves por Neisseria meningitidis (NM) se presentan habitualmente en pacientes pediátricos como meningitis, con o sin meningococcemia asociada [1][2][3] . Sin embargo, también se han visto formas atípicas de enfermedad meningocócica invasiva, como laringitis, pericarditis, artritis y neumonías, fuera del contexto de una meningitis meningocócica complicada [4][5][6][7][8][9][10] .…”
unclassified
“…ON can follow many viral infections (adenovirus, pertussis, mononucleosis, measles, mumps and chickenpox) and other infectious causes (bartonella, lyme, meningococcus, syphilis, toxocara and toxoplasma) [4,8]. Influenza virus live vaccines have also been advocated in association to ON [9,10] and recently after H1N1 vaccine [11].…”
Section: Similar and Contrasting Cases In The Literature And Discussionmentioning
confidence: 99%