Invasive Mediastinal Staging: Endobronchial Ultrasound, Endoscopic Ultrasound, and Mediastinoscopy

Block, Mark I.; Tarrazzi, Francisco

doi:10.1053/j.semtcvs.2013.10.001

Cited by 8 publications

(8 citation statements)

References 36 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cervical mediastinoscopy is the gold standard method for preoperative mediastinal lymph node staging in patients with lung cancer. The 2nd, 4th, and 7th station lymph nodes can be sampled by mediastinoscopy [24,25]. Nowadays, cervical mediastinoscopy is performed with the help of a videomediastinoscope and it is named "video-assisted mediastinoscopy (VAM)" or "video-assisted mediastinal lymphadenectomy (VAMLA)" depending on the application technique [26].…”

Section: Mediastinal Stagingmentioning

confidence: 99%

“…Endobronchial ultrasound (EBUS) and endoscopic ultrasound (EUS), which are parts of minimally invasive procedures, are successfully applied with high sensitivity and specificity for mediastinal staging. Combined application of EBUS and EUS allows sampling of lymph node stations numbered 2R, 2 L, 4R, 4 L, 7, 8, and 9 with the sensitivity of 86% (95% CI, 82-90%) [21,24,27].…”

Section: Mediastinal Stagingmentioning

confidence: 99%

See 1 more Smart Citation

The Role of Minimally Invasive Surgery in the Treatment of Lung Cancer

Batıhan¹,

Ceylan²

2021

Lung Cancer - Modern Multidisciplinary Management

View full text Add to dashboard Cite

Lobectomy plus regional lymph node dissection remains the gold standard treatment method in early-stage lung cancer. However, with the demonstration of the safety and efficacy of minimally invasive approaches, the expression of surgery in this statement, replaced by thoracoscopic anatomical lung resection. Clinical studies have demonstrated the superiority of VATS in terms of postoperative pain, drainage time, length of hospital stay, and complications, moreover, long-term oncologic results are similar or better than thoracotomy. Therefore, VATS lobectomy is the preferred surgical method in early-stage lung cancer. Different surgical techniques are available in VATS and can be modified according to the surgeon’s personal experience. Uniport can be applied as well as two or three port incisions. In this book section, I plan to focus on VATS lobectomy, technique-related tricks, complication management, and long-term oncologic results in early and locally advanced lung cancer.

show abstract

Section: Mediastinal Stagingmentioning

confidence: 99%

Section: Mediastinal Stagingmentioning

confidence: 99%

The Role of Minimally Invasive Surgery in the Treatment of Lung Cancer

Batıhan¹,

Ceylan²

2021

Lung Cancer - Modern Multidisciplinary Management

View full text Add to dashboard Cite

show abstract

“…Consequently, in routine practice a preoperative surgical staging procedure (i.e., VAMLA) as a consequence of a negative endosonography shall be provided. When it comes to prospective studies in experienced endosonography centers, it is of importance that the lack of improved sensitivity of conventional mediastinoscopy after well-performed negative endosonography has not to be equated with the possible sensitivity of VAMLA (as there is still a lack of appropriate studies) ( 28 , 40 , 41 ).…”

Section: Endoscopic Techniquesmentioning

confidence: 99%

Video-assisted mediastinoscopic lymphadenectomy (VAMLA) for staging & treatment of non-small cell lung cancer (NSCLC)

Hartert¹,

Tripsky²,

Huertgen³

2020

Mediastinum

View full text Add to dashboard Cite

Precise preoperative staging and restaging of mediastinal lymph nodes in patients with potentially resectable non-small cell lung cancer (NSCLC) is of supreme importance. Over the last years, algorithms on preoperative mediastinal staging incorporating imaging, endoscopic and surgical techniques have been widely published, offering more evidence concerning different mediastinal staging techniques. Current guidelines well define when and how to receive tissue confirmation in case of computed tomography (CT)-enlarged or positron emission tomography (PET)-positive mediastinal lymph nodes. Endosonography [(endoscopic bronchial ultrasonography/oesophageal ultrasonography (EBUS/EUS)] with fine needle aspiration still is the first choice (when accessible) since it is minimally invasive and has a high sensitivity to confirm mediastinal nodal disease. If negative, surgical staging with nodal dissection or biopsy is indicated. Video-assisted mediastinoscopic lymphadenectomy (VAMLA) and transcervical extended mediastinal lymphadenectomy (TEMLA) are preferred over conventional mediastinoscopy if a mediastinal R0-resection can be achieved. The mutual use of endoscopic and surgical staging effects highest accuracy. Straight surgical resection of tumors ≤3 cm (located within the external third of the lung) with systematic nodal dissection is justified as soon as there are no enlarged lymph nodes on CT-scan and once there is no nodal uptake on PET-CT. In case of central tumors and enlarged or FDG avid nodes regardless of cytological result, preoperative invasive mediastinal staging is indicated to rule out mediastinal nodal spread. However, accuracy needed in preoperative nodal staging has been under continuous debate ever since and with the advent of immunotherapy is right now intensely revived. During the last two decades VAMLA has been growing up from being a merely staging tool to an expert-recognized therapeutic tool in the context of minimal invasive lung cancer resection.

show abstract

“…A large number of publications recently summarized in a meta-analysis (7) Complications of EBUS are similar to those of bronchoscopy and conventional transbronchial needle aspirate and include rare instances of pneumothorax and mediastinitis (7). EUS offers some technical advantages compared with EBUS such as higher quality and wider field of ultrasound image and less air artefact (4). The needle tends to pass more easily through soft esophageal tissue compared with the cartilaginous airway wall.…”

Section: Endoscopic Ultrasoundmentioning

confidence: 99%

Mediastinal Staging for Lung Cancer

Gelberg

Grondin

Tremblay

2014

Canadian Respiratory Journal

View full text Add to dashboard Cite

Staging of the mediastinal and hilar lymph nodes plays a crucial role in identifying the best treatment option for patients with confirmed or suspected lung cancer and, in many cases, can simultaneously confirm a diagnosis of cancer. Noninvasive modalities, such as computed tomography (CT), positron emission tomography (PET) and PET-CT, are an important first step in this assessment. Ultimately, invasive staging is frequently required to confirm or rule out the presence of metastatic disease within the lymph nodes. The present focused review describes and compares noninvasive and invasive modalities for mediastinal staging in lung cancer.

show abstract

Invasive Mediastinal Staging: Endobronchial Ultrasound, Endoscopic Ultrasound, and Mediastinoscopy

Cited by 8 publications

References 36 publications

The Role of Minimally Invasive Surgery in the Treatment of Lung Cancer

The Role of Minimally Invasive Surgery in the Treatment of Lung Cancer

Video-assisted mediastinoscopic lymphadenectomy (VAMLA) for staging & treatment of non-small cell lung cancer (NSCLC)

Mediastinal Staging for Lung Cancer

Contact Info

Product

Resources

About