2010
DOI: 10.1155/2010/585187
|View full text |Cite
|
Sign up to set email alerts
|

Invasive Group A Streptococcal Disease: Management and Chemoprophylaxis

Abstract: Given the potentially devastating consequences of severe invasive group A streptococcal disease, attention has been directed toward the role of chemoprophylaxis and the optimization of management strategies. In response to this issue, Canadian guidelines were previously developed. However, the uptake of these recommendations is variable across Canada. The present document summarizes key components of the recommendations for use by Canadian physicians. The importance of penicillin in the treatment of group A st… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

0
12
0
3

Year Published

2014
2014
2021
2021

Publication Types

Select...
5

Relationship

0
5

Authors

Journals

citations
Cited by 15 publications
(15 citation statements)
references
References 12 publications
(13 reference statements)
0
12
0
3
Order By: Relevance
“…However, this may still be low given the potential benefits of antitoxin treatment with clindamycin for severe invasive GAS infections previously reported in one study 25 33 34…”
Section: Discussionmentioning
confidence: 99%
“…However, this may still be low given the potential benefits of antitoxin treatment with clindamycin for severe invasive GAS infections previously reported in one study 25 33 34…”
Section: Discussionmentioning
confidence: 99%
“…An exception is Canada, where invasive group A streptococcal infection is reportable in all provinces and territories . In 2006, guidelines were introduced, which recommended that chemoprophylaxis should be offered to all close contacts of a confirmed case of severe group A streptococcus .…”
Section: Discussion and Review Of The Literaturementioning
confidence: 99%
“…An exception is Canada, where invasive group A streptococcal infection is reportable in all provinces and territories . In 2006, guidelines were introduced, which recommended that chemoprophylaxis should be offered to all close contacts of a confirmed case of severe group A streptococcus . In particular, the guidelines recommend the administration of a first‐generation cephalosporin to household contacts, arguing that penicillin is less effective in eradicating GAS colonisation than the cephalosporins .…”
Section: Discussion and Review Of The Literaturementioning
confidence: 99%
See 1 more Smart Citation
“…1 Canadian guidelines suggest chemoprophylaxis be offered to all close contacts of a confirmed case of iGAS, including those exposed from 7 days pre-onset of symptoms in the case to 24 h after the initiation of antimicrobial therapy. 2 Current UK guidelines also suggest if there are two or more cases of iGAS within a 30-day period, that household contacts should be issued chemoprophylaxis. 3 Current Queensland Communicable Disease Control Guidance records iGAS as a notifiable condition; however, chemoprophylaxis is not routinely recommended.…”
mentioning
confidence: 99%