Invasive fungal infection in patients with systemic lupus erythematosus: Experience from a single institute of Northern China

Fan, Yu–Chen; Li, Wengang; Zheng, Ming‐Hua; Gao, Wei; Zhang, Yuanyuan; Song, Lijun

doi:10.1016/j.gene.2012.06.059

Cited by 19 publications

(16 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Also patients with systemic lupus erythematosus (SLE), which are treated with glucocorticoids and other immunosuppressive agents, have an increased risk for invasive fungal infections (IFI), which are predominantly caused by Candida spp. (Fan et al, 2012).…”

Section: General Risk Factors For Candida Infectionsmentioning

confidence: 99%

“…EMBO Mol Med (2013) patients with systemic lupus erythematosus (SLE), which are treated with glucocorticoids and other immunosuppressive agents, have an increased risk for invasive fungal infections (IFI), which are predominantly caused by Candida spp. (Fan et al, 2012). Not only a weakened immune system increases the risk for Candida infections, also the extent to which individuals are colonized with pathogens plays a significant role in the development of candidiasis.…”

Section: Nf-κbmentioning

confidence: 99%

See 1 more Smart Citation

Genetic susceptibility to Candida infections

et al. 2013

View full text Add to dashboard Cite

Candida spp. are medically important fungi causing severe mucosal and life-threatening invasive infections, especially in immunocompromised hosts. However, not all individuals at risk develop Candida infections, and it is believed that genetic variation plays an important role in host susceptibility. On the one hand, severe fungal infections are associated with monogenic primary immunodeficiencies such as defects in STAT1, STAT3 or CARD9, recently discovered as novel clinical entities. On the other hand, more common polymorphisms in genes of the immune system have also been associated with fungal infections such as recurrent vulvovaginal candidiasis and candidemia. The discovery of the genetic susceptibility to Candida infections can lead to a better understanding of the pathogenesis of the disease, as well as to the design of novel immunotherapeutic strategies. This review is part of the review series on host-pathogen interactions. See more reviews from this series.

show abstract

Section: General Risk Factors For Candida Infectionsmentioning

confidence: 99%

Section: Nf-κbmentioning

confidence: 99%

Genetic susceptibility to Candida infections

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Bir kohort çalışmasında, kandidemili 107 hastanın %50'sinde kısa süre önce bir cerrahi girişimin bulunduğu vurgulanmıştır (9) . Ayrıca, glukokortikoid ve diğer immünosüpresif ilaç tedavisi alan sistemik lupus eritematozus hastalarında, sıklık-la Candida türlerinin neden olduğu invazif mantar enfeksiyonlarının riski artmıştır (10) . Nötropeni saptanan AIDS ve onkoloji hastaları hemen daima orofaringeyal ve özefagiyal kandidoz geçirirler (11,12) .…”

Section: Epi̇demi̇yoloji̇unclassified

Candida ve Kandidoz: Epidemiyoloji, Tanı, Tedavi, Antifungal İlaç Direnci ve Konağın Genetik Yatkınlığında Güncel Durum

Seyedmousavi¹,

İlkit²,

Durdu³

et al. 2015

TMCD

View full text Add to dashboard Cite

“…Doenças fúngicas invasivas ocorrem mais freqüentemente em pacientes imunodeprimidos com câncer hematológico, transplante de medula óssea 31 e infecção pelo HIV 43 . A literatura referente a IFI em adultos com LES consiste de relatos de casos e séries de casos, com prevalência variando entre 0,64 e 4,8% 43,44,45,46,47,48 , semelhante à presente população estudada com lúpus de início na faixa etária pediátrica.…”

Section: Objetivosunclassified

“…Assim como nesta população estudada, altos escores de atividade da doença também foram relatados no início das IFI em pacientes adultos com LES 41,44,45,46 .…”

Section: Objetivosunclassified

Infecções fúngicas invasivas em pacientes com lúpus eritematoso sistêmico juvenil

Silva¹

View full text Add to dashboard Cite

, baiano incansável e patriarca da minha Família Reumatológica Paulistana, a quem tenho grande estima e admiração. Obrigado pela amizade (inclusive pelas conversas discordantes que tanto geraram ensinamento e me fizeram crescer), assim como pelo estímulo constante aos estudos, orientação e realização deste projeto. Ao Dr. Carlos Nobre Rabelo Júnior, meu "irmão reumático" mais velho e eterno mestre, responsável direto pela minha decisão de fazer Reumatologia Pediátrica. Obrigado pela amizade, paciência, apoio incondicional, confiança no meu trabalho e no meu potencial (até quando eu mesmo chego a ficar em dúvida), além da disponibilidade e prontidão diuturnas para me substituir nas inúmeras vezes que precisei ir a São Paulo com o intuito de concretizar esta tese. À amiga e braço-direito Mariana Paes Leme Ferriani, que esteve por perto durante toda a realização deste projeto, dividindo os sucessos e as angústias, desde à criação do banco de dados até a redação final. Aos chefes, assistentes e pós-graduandos de todos os 10 serviços de

show abstract

Invasive fungal infection in patients with systemic lupus erythematosus: Experience from a single institute of Northern China

Cited by 19 publications

References 21 publications

Genetic susceptibility to Candida infections

Genetic susceptibility to Candida infections

Candida ve Kandidoz: Epidemiyoloji, Tanı, Tedavi, Antifungal İlaç Direnci ve Konağın Genetik Yatkınlığında Güncel Durum

Infecções fúngicas invasivas em pacientes com lúpus eritematoso sistêmico juvenil

Contact Info

Product

Resources

About