Invasive electrical impedance myography at different levels of contraction of gastrocnemius muscle of rat

et al. 2023

Front. Aging Neurosci.

Aging is a non-modifiable risk factor for stroke and the global burden of stroke is continuing to increase due to the aging society. Muscle dysfunction, common sequela of stroke, has long been of research interests. Therefore, how to accurately assess muscle function is particularly important. Electrical impedance myography (EIM) has proven to be feasible to assess muscle impairment in patients with stroke in terms of micro structures, such as muscle membrane integrity, extracellular and intracellular fluids. However, EIM alone is not sufficient to assess muscle function comprehensively given the complex contributors to paretic muscle after an insult. This article discusses the potential to combine EIM and other common quantitative methods as ways to improve the assessment of muscle function in stroke survivors. Clinically, these combined assessments provide not only a distinct advantage for greater accuracy of muscle assessment through cross-validation, but also the physiological explanation on muscle dysfunction at the micro level. Different combinations of assessments are discussed with insights for different purposes. The assessments of morphological, mechanical and contractile properties combined with EIM are focused since changes in muscle structures, tone and strength directly reflect the muscle function of stroke survivors. With advances in computational technology, finite element model and machine learning model that incorporate multi-modal evaluation parameters to enable the establishment of predictive or diagnostic model will be the next step forward to assess muscle function for individual with stroke.

Section: Combination Of Eim and Contractile Property Assessmentmentioning

confidence: 73%

Section: Contractile Property Assessmentmentioning

confidence: 99%

Electrical impedance myography combined with quantitative assessment techniques in paretic muscle of stroke survivors: Insights and challenges

Gong

et al. 2023

Front. Aging Neurosci.

“…On the other hand, changes in the X value are related to changes in the features of the cell membrane and layers of tissue ( 36 ). Coutinho et al ( 37 ) suggested that changes in X were likely to be caused by changes in the features of the cellular membranes. In this study, the R and Z values increased significantly at 5 kHz in the CLBP group.…”

Section: Discussionmentioning

confidence: 99%

Electrical Properties of Lumbar Paraspinal Muscles in Young Adults With and Without Chronic Low Back Pain Based on Electrical Impedance Myography: A Cross-Sectional Study

Zheng

et al. 2022

Front. Neurol.

BackgroundLumbar paraspinal muscle (LPM) is important in spinal stabilization in patients with chronic low back pain (CLBP). However, the electrical properties of LPM in patients with CLBP remain unclear. Electrical impedance myography (EIM) is a novel and non-invasive technique that provides a simple quantitative evaluation of electrical properties of the LPM.PurposeThis study aimed to apply EIM to assess the electrical properties of the LPM between patients with CLBP and healthy control (HC).MethodsThirty participants (15 CLBP participants; 15 healthy controls) were enrolled in the study. Participants in the CLBP group were asked to complete the visual analog scale (VAS), Oswestry Disability Index (ODI), and Roland–Morris Disability Questionnaire (RDQ) to assess the pain intensity and disability in daily life. Independent sample t-tests were adopted to analyze the basic characteristics between the two groups. At 5, 50, 100, and 200 kHz current frequencies, the electrical properties were measured on each side of the LPM. The EIM parameters of resistance (R), reactance (X), phase angle (PA), and Z value were analyzed by one-way analysis of variance (ANOVA), with age as covariate. Spearman's rank correlation coefficient analysis was applied to explore the relationships between the questionnaires and the EIM parameters.ResultsThe R and Z values of bilateral LPM in the CLBP group were significantly larger than those in the HC group; the PA decreased and the X did not change at these four tested current frequencies. At 5 kHz, Z and R on the right side were non-significantly different between patients and HCs. Correlation analysis showed that at 50 kHz, ODI and RDQ scores correlated negatively with the R of the bilateral LPM (r = 0.523, r = 0.581, respectively; p < 0.05). RDQ scores correlated positively with the PA of the right LPM (r = 0.521, p < 0.05).ConclusionThe electrical properties of the bilateral LPM differed between CLBP participants and healthy individuals, regardless of the different frequencies used. These altered electrical properties of the LPM in the patients with CLBP correlated to some extent with disability in daily life.

“…Changes in X value are related to changes in features of the cell membrane and layers of tissue [28]. Coutinho et al [29] suggested changes in reactance were likely brought about by changes in the features of the cellular membranes.…”

Section: Discussionmentioning

confidence: 99%

Different Electrical Properties of Paraspinal Muscle in Young Adults With Non-specific Chronic Low Back Pain and Healthy Individuals by Electrical Impedance Myography: A Cross-sectional Study

Fan

et al. 2021

Preprint

BackgroundNon-specific chronic low back pain (NSCLBP) is a multifactor disorder with high prevalence rate of people all around the world. Lumbar paraspinal muscle (LPM) plays an important role of spine stabilization. However, the electrical properties of LPM in the patients were unclear. Aim to explore the electrical properties of bilateral LPM between patients with NSCLBP and healthy controls (HC), the study was designed to applied electrical impedance myography (EIM) technique to measure the LPM.MethodsA total of thirty participates (15 in NSCLBP group, 15 in HC group) were instructed to have each side of LPM measured at the rest state and the maximum volunteer contraction (MVC) state. Then measured the EIM parameters of LPM at L4/5 level by a multi-frequency device. Each measurement repeated three times. The EIM parameters at 50 kHz, 100 kHz, 200 kHz current frequencies were enrolled into the statistical analysis.ResultsAt the three current frequencies, parameters in the right side of LPM had not significantly difference from the left (P>0.05, respectively). Resistance (R) of LPM in NSCLBP group was larger than that in HC group (P<0.05, respectively), phase angle (PA) in NSCLBP group was smaller than that in HC group (P<0.05, respectively) and there was no difference of the reactance value between the two groups (P>0.05, respectively). At 50 kHz, relationships between the EIM parameters and geometric parameters of LPM were not significant in NSCLBP group or HC group (P>0.05, respectively).ConclusionThe electrical properties of bilateral LPM in young adults with NSCLBP were different from those of healthy individuals regardless of any current frequency. The ultrasound parameters of LPM, however, showed no significant difference between young patients with NSCLBP and healthy participants. EIM measurement might be more sensitive than rehabilitative ultrasound for NSCLBP in young adults.Trial registrationThe Chinese Clinical trial registration number: ChiCTR2100043113.