Invasive Amebiasis as an Emerging Parasitic Disease in Patients With Human Immunodeficiency Virus Type 1 Infection in Taiwan

Hung, Chien‐Ching; Deng, Hung-Yin; Hsiao, Wei-Hung; Hsieh, Szu‐Min; Hsiao, Chin‐Fu; Chen, Mao-Yuan; Chang, Shan-Chwen; Su, Kang‐Yi

doi:10.1001/archinte.165.4.409

Cited by 92 publications

(63 citation statements)

References 28 publications

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“…Some opportunistic protozoan parasites, such as Cryptosporidium parvum, Isospora belli, and microsporídia contribute to chronic diarrhea, with resultant loss of weight in HIV/AIDS patients 3 . Besides, protozoa such as Giardia lamblia and Entamoeba histolytica and the helminths Strongyloides stercoralis, Ascaris lumbricoides, and Ancylostoma duodenale [4][5][6] are regarded as the main pathogens that affect these patients.…”

Section: Resultsmentioning

confidence: 99%

Enteric parasites in HIV-1/AIDS-infected patients from a Northwestern São Paulo reference unit in the highly active antiretroviral therapy era

Cardoso

Galisteu

Júnior

et al. 2011

Rev. Soc. Bras. Med. Trop.

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Introduction:We describe the epidemiology of intestinal parasites in patients from an AIDS reference service in Northeastern São Paulo, Brazil. Methods: Retrospective evaluation was done for all HIV-1/AIDS-positive patients whose Hospital de Base/São José do Rio Preto laboratorial analysis was positive for enteroparasites after diagnosis of HIV-1 infection, from January 1998 to December 2008. Statistical analysis was performed using the R statistical software version 2.4.1. The level of significance adopted was 5%. Results: The most frequent protozoan was Isospora belli (4.2%), followed by Giardia lamblia (3.5%), Entamoeba coli (2.8%), and Cryptosporidium parvum (0.3%). Ancylostoma duodenale (1.4%) was the most frequently detected helminth, while Taenia saginata and Strongiloides stercoralis were found in 0.7% of the samples. The results showed that diarrhea was significantly associated with giardiasis and isosporiasis. However, no association was observed between CD4 + cell counts, viral load, and the characteristics of any particular parasite. Conclusions: Our data may be useful for further comparisons with other Brazilian regions and other developing countries. The data may also provide important clues toward improving the understanding, prevention, and control of enteric parasites around the world. Keywords: Epidemiology. HIV-1. AIDS. Enteroparasites. HAART. Brazil. RESUMOIntrodução: Descrevemos a epidemiologia de enteroparasitoses em pacientes de um serviço de referência de AIDS, no noroeste paulista, Brasil. Métodos: Durante o período de janeiro de 1998 a dezembro de 2008, foi realizado este estudo retrospectivo por meio da análise dos prontuários dos pacientes diagnosticados com HIV-1/AIDS atendidos no Ambulatório de Doenças Infecto-Parasitárias do Hospital de Base, São José do Rio Preto, São Paulo. As análises estatísticas foram realizadas usando a versão 2.4.1 do software estatístico R. O nível de significância adotado foi de 5%. Resultados: O protozoário mais frequente foi o Isospora belli (4,2%), seguido da Giardia lamblia (3,5%), Entamoeba coli (2,8%) e Criptosporidium parvum (0,3%). O Ancylostoma duodenalis (1,4%) foi o helminto mais detectado, enquanto a Taenia saginata e o Strongiloides stercoralis foram observados em 0,7% das amostras. Os resultados mostraram que a diarreia foi significativamente associada com giardíase e isosporíase. Entretanto, nenhuma associação foi observada entre as contagens de células T CD4 + , carga viral e da característica de qualquer parasita em particular. Conclusões: Nossos dados podem ser úteis para futuras comparações com outras regiões do Brasil e outros países em desenvolvimento. Os dados também podem fornecer pistas importantes para a melhoria da compreensão, prevenção e controle de parasitas entéricos em todo o mundo. Palavras-chaves: Epidemiologia. HIV-1. AIDS. Enteroparasitas. HAART. Brasil.

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Section: Resultsmentioning

confidence: 99%

Enteric parasites in HIV-1/AIDS-infected patients from a Northwestern São Paulo reference unit in the highly active antiretroviral therapy era

Cardoso

Galisteu

Júnior

et al. 2011

Rev. Soc. Bras. Med. Trop.

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“…Según algunos autores, los individuos con el virus de la inmunodeficiencia humana (VIH) también son un grupo de riesgo 12 . Sin embargo, en los países del Occidente, aunque de 20% a 30% de los hombres homosexuales están infectados con E. dispar, la amebiasis invasiva es muy rara en pacientes con el VIH 21 . En dos estudios realizados en México, ninguno de los pacientes VIH positivos infectados con E. histolytica presentaba síntomas atribuibles al parásito 22 .…”

Section: La Epidemiología De La Amebiasisunclassified

Amebiasis: aspectos clínicos, terapéuticos y de diagnóstico de la infección

Chacín-Bonilla

2013

Rev. méd. Chile

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609artículos de revisión L a amebiasis se considera como una causa importante de morbilidad y mortalidad en el mundo y constituye dentro de las enfermedades de origen parasitario, especialmente en el mundo en desarrollo, la tercera causa de muerte después de la malaria y la esquistosomiosis 1,2 . El reconocimiento de Entamoeba dispar y Entamoeba moshkovskii en humanos ha complicado más el diagnóstico de E. histolytica. Estas tres especies son morfológicamente indistinguibles y las dos primeras se consideran comensales. Sin embargo, estudios recientes sugieren que puedan desempeñar un papel patógeno. En Bangladesh e India, E. dispar y E. moshkovskii se observaron asociadas con síntomas gastrointestinales 3 y se ha demostrado que E. dispar produce lesiones intestinales y hepáticas en conejillos de Indias 4 . La distribución mundial y la magnitud de la infección de estas tres especies no son conocidas, ya que la mayoría de los diagnósticos, especialmente en el tercer mundo, se siguen basando en la observación microscópica lo que no permite diferenciarlas. Los datos actuales sugieren que E. dispar es 10 veces más común que E. histolytica en individuos asintomáticos pero las prevalencias locales de ambas especies varían significativamente 1 . No todas las infecciones con E. histolytica conducen a la enfermedad y sólo una de cada 10 infecciones progresan hacia la enfermedad 3 . El objetivo de esta revisión es describir y discutir los avances recientes en la amebiasis con énfasis en los aspectos clínicos, de diagnóstico y manejo de la infección. La epidemiología de la amebiasisLa amebiasis es común y ampliamente diseminada, pero la prevalencia varía según las áreas geográficas. Alrededor de 50 millones de personas

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“…6 It has been previously reported that stool protozoan carriage occurs at increased rates in men who have sex with men (MSM). 7 Studies from East Asia have recognized E. histolytica as an emerging pathogen in MSM, [8][9][10][11] where sexual activity, especially oro-anal contact, is suggested to be the mode of transmission. 12 There have also been increasing reports from North America and Europe of invasive disease in the MSM population.…”

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confidence: 99%

Seroprevalence of Entamoeba histolytica Infection among Men Who Have Sex with Men in Sydney, Australia

James¹,

Barratt²,

Marriott³

et al. 2010

The American Society of Tropical Medicine and Hygiene

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A retrospective analysis was undertaken to determine the seroprevalence of Entamoeba histolytica infection in Sydney, Australia. Using an enzyme-linked immunosorbent assay, 429 high risk human immunodeficiency virus (HIV)-infected men who have sex with men (MSM), 446 low risk HIV-uninfected MSM, and 456 HIV-uninfected controls were assessed. Seroprevalence rates were 5.13% for the high risk HIV-infected MSM group, 0.22% for the low risk HIV-uninfected MSM group, and 0.44% for the control group. We found that high risk HIV-infected MSM have a significantly greater seroprevalence of E. histolytica with a relative risk of 22.87, when compared with low risk HIV-uninfected MSM and 11.69 when compared with controls. These findings show that in Sydney, sexually active HIV-infected MSM are at greater risk of developing amoebic disease caused by E. histolytica than HIV-uninfected MSM and the general population.

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Invasive Amebiasis as an Emerging Parasitic Disease in Patients With Human Immunodeficiency Virus Type 1 Infection in Taiwan

Abstract: Persons infected with HIV in Taiwan are at increased risk for invasive amebiasis and exhibit a relatively high frequency of elevated antibody titers and intestinal colonization with E histolytica.

Cited by 92 publications

References 28 publications

Enteric parasites in HIV-1/AIDS-infected patients from a Northwestern São Paulo reference unit in the highly active antiretroviral therapy era

Enteric parasites in HIV-1/AIDS-infected patients from a Northwestern São Paulo reference unit in the highly active antiretroviral therapy era

Amebiasis: aspectos clínicos, terapéuticos y de diagnóstico de la infección

Seroprevalence of Entamoeba histolytica Infection among Men Who Have Sex with Men in Sydney, Australia

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