Intubating Conditions and Onset of Action After Rocuronium, Vecuronium, and Atracurium in Young Children

A Study of Priming Technique of Rocuronium in Facilitating Intubation

“…This result agrees with the findings of Scheiber et al 13 , who observed good to excellent intubating conditions after rocuronium 0.6 mg/kg can be obtained within 30-60 seconds in young children.…”

“…Rocuronium induced neuromuscular block develops faster at the adductor muscles of larynx than at the adductor pollicis muscle, so it appears that intubation may be performed before complete block is achieved as measured at the thumb 12 . In a study conducted by 13 observed that, at the time of intubation, the neuromuscular block achieved at the adductor pollicis muscle was incomplete in most patients. They expressed their opinion that, when conducting studies of intubating conditions, only frequent-interval intubation attempts begun sufficiently early can development of optimum laryngeal conditions.…”

Comparison of rocuronium and suxamethonium for rapid tracheal intubation in children

“…Rocuronium, a nondepolarizing neuromuscular relaxant with a fast onset of action, has been shown to provide good to excellent intubating conditions within 30–60 s in young children (4,5). Hence, it may be an attractive alternative to suxamethonium without the associated side‐effects.…”

The influence of fentanyl vs. s-ketamine on intubating conditions during induction of anaesthesia with etomidate and rocuronium

“…Many reports claim that rocuronium is an acceptable alternative to succinylcholine for rapid‐sequence induction, even if it is used in a lower dosage (0.6 mg kg −1 ) to avoid a prolonged action. This result may not only be explained by the effect of rocuronium itself [17–21] but also by the interaction of combined anaesthetic agents [22]. Nevertheless, often no complete neuromuscular blockade is found after 60 s using relaxometry measurements [2,18–20].…”