In this paper we derive a Heisenberg-type uncertainty principle for the continuous Clifford wavelet transform. A brief review of Clifford algebra/analysis, wavelet transform on R and Clifford-Fourier transform and their proprieties has been conducted. Next, such concepts have been applied to develop an uncertainty principle based on Clifford wavelets.2000 Mathematics Subject Classification. 30G35, 42C40, 42B10, 15A66.