Introductory Chapter: One-Stop Infertility Evaluation Unit

Darwish, Atef M.; Mohamed, Essam-Eldn

doi:10.5772/intechopen.69631

Cited by 2 publications

(2 citation statements)

References 32 publications

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“…2 Infertility has been ranked as the fifth global disability in females. 3 It is anticipated that globally 60-80 million couples face the problem to conceive every year. 4 The prevalence of infertility in Pakistan has been estimated which is about 21.9%.…”

Section: Introductionmentioning

confidence: 99%

Thyroid Disorders;

Rahman

Saeed

Zia

et al. 2019

TPMJ

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Infertility has been considered as a worldwide global health issue. It is a human nature that every couple wants to have children so that the relationship can become stronger. Defect in thyroid hormone levels is one of the factors which can lead to reproductive cycle disorders and thus infertility results. Objectives: The purpose of current study was to investigate the levels of thyroid hormones in primary infertile and fertile females in order to evaluate the prevalence of thyroid disordsers. Study Design: Case control study. Place of Study: Outdoor of gynecology department of Madinah Teaching Hospital, Faisalabad. Duration of Study: 6 months from July to December 2017. Material and Methods: The study enrolled total 91 females of reproductive age 20-35 years which included 45 primary infertile females and 46 fertile females. They were divided into two groups. Group I: case/primary infertile women group (n= 45) and Group II: control /fertile females group (n= 46). Data was collected by taking history and clinical examination. Hormonal profile including fT3, fT4 and TSH was done by means of chemiluminescentimmunoassay. Results were analyzed by using SPSS version 20. Results: Most of the infertile females were euthyroid and hyperthyroidism was the most common thyroid disorder. The prevalence of hypothyroidism and hyperthyroidism was about 9.3% and 26.7% respectively. The p-value showed the non-significant difference in the levels of fT3, fT4 and TSH between primary infertile and fertile females.Significant positive correlation between fT3 and fT4 while non-significant negative correlation was observed between fT3 & TSH and fT4& TSH in primary infertile females. Conclusion: Infertile females with menstrual irregularities should be advised thyroid profile in order to avoid other unnecessary investigations. Evaluation of thyroid status in the infertile couple is not only important but also easy because its treatment is very simple and often has revocable effects on subfertility.

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Section: Introductionmentioning

confidence: 99%

Thyroid Disorders;

Rahman

Saeed

Zia

et al. 2019

TPMJ

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“…Recently, we outlined a one-stop infertility evaluation unit principle to cut short lengthy infertility management protocols. 20 Practically, we face a lot of PCOS cases treated by repeated high-dose courses of induction of ovulation and later on proved to have a missed cause of infertility like pelvic endometriosis, tiny peritubal factors like paratubal cysts, lipomesosalpnix or fine adhesions in the pouch of Douglas.…”

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confidence: 99%

Laparoscopic ovarian drilling-plus: a one-stop management approach for PCO-associated infertility

Darwish

Kamel

Othman

et al. 2017

Int J Reprod Contracept Obstet Gynecol

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INTRODUCTIONPolycystic ovarian syndrome (PCOS) is the commonest hyperandrogenic disorder in women and one of the most common causes of anovulatory infertility, with an estimated prevalence of 4-7% worldwide. 1 It is an overdiagnosed and disproportionately treated condition.Lifestyle modification, weight loss, and exercise form the first line of treatment in infertile women with PCOS. 2The recommended first-line drug for ovulation induction remains clomiphene citrate (CC), while metformin is helpful in cases with glucose intolerance, or those with a BMI >35 kg/m. 3 ABSTRACT Background:The current study aims to estimate additional values of laparoscopic intervention for diagnosis and treatment of concomitant pelvic pathologies among infertile women with clomiphene-resistant polycystic ovarian syndrome (PCOS) subjected to laparoscopic ovarian drilling (LOD) in comparison to non-PCOS infertile women subjected to diagnostic/therapeutic laparoscopy. Methods: A prospective cross sectional observational study was carried out in the Endoscopic unit of a tertiary care university hospital. The study included 232 infertile women planned for laparoscopy were divided into a study group A (116 cases) with clomiphene-resistant PCOS and a control group B (116 cases) without PCOS. Each group was further subdivided into two subgroups according to the presence and absence of risk factors (RF) for adhesion formation. Diagnostic/operative laparoscopy was done. The main study outcome was the prevalence of any pelvic abnormalities seen during laparoscopy. Results: Both groups showed insignificant difference regarding socio-demographic history and basic data. Laparoscopy detected pelvic pathologies in 44 cases (37.9%) and 86 cases (74.1%) in both groups respectively. In group A, we diagnosed pelvic pathologies in 29 (32.6%) and 15 (55.6%) cases with and without RF respectively while in group B they were diagnosed in 76 (84.4%) and 10 (38.5%) cases with and without RF respectively. If compared to women with unexplained infertility, PCO patients without risk factors have an insignificant but higher prevalence of pelvic abnormalities. All concomitant pelvic pathologies in both groups were treated on a one-stop (see and treat) basis. Conclusions: Detection and proper management of associated pelvic pathologies at laparoscopy is a valuable additional advantage of LOD particularly in women with positive risk factors. LOD plus see and treat associated pathologies is a time saving and prompt management approach for women with PCO-associated infertility.

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Introductory Chapter: One-Stop Infertility Evaluation Unit

Cited by 2 publications

References 32 publications

Thyroid Disorders;

Thyroid Disorders;

Laparoscopic ovarian drilling-plus: a one-stop management approach for PCO-associated infertility

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